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Long-term characterization of neural electrodes based on parylene-caulked polydimethylsiloxane substrate

Title
Long-term characterization of neural electrodes based on parylene-caulked polydimethylsiloxane substrate
Authors
Jeong, J[Jeong, Jinmo]Chou, N[Chou, Namsun]Kim, S[Kim, Sohee]
DGIST Authors
Kim, S[Kim, Sohee]
Issue Date
2016-06
Citation
Biomedical Microdevices, 18(3)
Type
Article
Article Type
Article
Keywords
Biomedical ApplicationsConvergence of Numerical MethodsElectrical StabilityElectro-Chemical ElectrodesElectro-Chemical Impedance Spectroscopy (EIS)Electrochemical Impedance Spectroscopy (EIS)ElectrodesImplantable ElectrodesMechanical PropertiesMedical ApplicationsMicrochannelsNeural ElectrodeParyleneParylene-Caulked PDMS (PC-PDMS)ParylenesPhosphate-Buffered Saline SolutionsPolydimethylsiloxane (PDMS)SiliconesStabilityStretchabilitySurface ElectrodeTensile TestingWater Absorption
ISSN
1387-2176
Abstract
This study investigates the mechanical and long-term electrical properties of parylene-caulked polydimethylsiloxane (PDMS) as a substrate for implantable electrodes. The parylene-caulked PDMS is a structure where particles of parylene fill the porous surface of PDMS. This material is expected to have low water absorption and desirable mechanical properties such as flexibility and elasticity that are beneficial in many biomedical applications. To evaluate the mechanical property and electrical stability of parylene-caulked PDMS for potential in-vivo uses, tensile tests were conducted firstly, which results showed that the mechanical strength of parylene-caulked PDMS was comparable to that of native PDMS. Next, surface electrodes based on parylene-caulked PDMS were fabricated and their impedance was measured in phosphate-buffered saline (PBS) solution at 36.5 °C over seven months. The electrodes based on parylene-caulked PDMS exhibited the improved stability in impedance over time than native PDMS. Thus, with improved electrical stability in wet environment and preserved mechanical properties of PDMS, the electrodes based on parylene-caulked PDMS are expected to be suitable for long-term in-vivo applications. © 2016, Springer Science+Business Media New York.
URI
http://hdl.handle.net/20.500.11750/1302
DOI
10.1007/s10544-016-0065-z
Publisher
Springer
Related Researcher
  • Author Kim, So Hee Neural Interfaces & MicroSystems Lab
  • Research Interests Neural interface; Neural stimulation; Bio MEMS; Stretchable electronics; Numerical simulation of implant-body interactions
Files:
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Collection:
Robotics EngineeringNeural Interfaces & MicroSystems Lab1. Journal Articles
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