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PI(4,5)P-2 and L-type Ca2+ Channels Partner Up to Fine-Tune Ca2+ Dynamics in beta Cells

Title
PI(4,5)P-2 and L-type Ca2+ Channels Partner Up to Fine-Tune Ca2+ Dynamics in beta Cells
Authors
Suh, BC[Suh, Byung-Chang]Yeon, JH[Yeon, Jun-Hee]Park, CG[Park, Cheon-Gyu]
DGIST Authors
Suh, BC[Suh, Byung-Chang]; Yeon, JH[Yeon, Jun-Hee]; Park, CG[Park, Cheon-Gyu]
Issue Date
2016-07-21
Citation
Cell Chemical Biology, 23(7), 753-755
Type
Article
Article Type
Short Survey; Editorial Material
ISSN
2451-9448
Abstract
The PI(4,5)P2 level in the plasma membrane is dynamically regulated by cytoplasmic ATP production and receptor-mediated transmembrane signaling cascades. In this issue of Cell Chemical Biology, Xie et al. (2016) use optogenetics to micro-manipulate membrane PI(4,5)P2 and reveal how acute PI(4,5)P2 changes can alter intracellular Ca2+ dynamics and insulin secretion in pancreatic β cells. © 2016 Elsevier Ltd
URI
http://hdl.handle.net/20.500.11750/1634
DOI
10.1016/j.chembiol.2016.07.001
Publisher
Cell Press
Related Researcher
Files:
There are no files associated with this item.
Collection:
Brain and Cognitive SciencesETC1. Journal Articles


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