Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Hwang, Jae Youn | - |
dc.contributor.author | Kang, Bong Jin | - |
dc.contributor.author | Lee, Changyang | - |
dc.contributor.author | Kim, Hyung Ham | - |
dc.contributor.author | Park, Jinhyoung | - |
dc.contributor.author | Zhou, Qifa | - |
dc.contributor.author | Shung, K. Kirk | - |
dc.date.available | 2017-07-11T06:01:20Z | - |
dc.date.created | 2017-04-10 | - |
dc.date.issued | 2015-01 | - |
dc.identifier.issn | 2156-7085 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11750/2944 | - |
dc.description.abstract | We demonstrate a novel non-contact method: acoustic radiation force impulse microscopy via photoacoustic detection (PA-ARFI), capable of probing cell mechanics. A 30 MHz lithium niobate ultrasound transducer is utilized for both detection of phatoacoustic signals and generation of acoustic radiation force. To track cell membrane displacements by acoustic radiation force, functionalized single-walled carbon nanotubes are attached to cell membrane. Using the developed microscopy evaluated with agar phantoms, the mechanics of highly- and weakly-metastatic breast cancer cells are quantified. These results clearly show that the PA-ARFI microscopy may serve as a novel tool to probe mechanics of single breast cancer cells. © 2014 Optical Society of America. | - |
dc.publisher | OSA - The Optical Society | - |
dc.title | Non-contact acoustic radiation force impulse microscopy via photoacoustic detection for probing breast cancer cell mechanics | - |
dc.type | Article | - |
dc.identifier.doi | 10.1364/BOE.6.000011 | - |
dc.identifier.scopusid | 2-s2.0-84942373495 | - |
dc.identifier.bibliographicCitation | Biomedical Optics Express, v.6, no.1, pp.11 - 22 | - |
dc.description.isOpenAccess | FALSE | - |
dc.subject.keywordPlus | FUNCTIONALIZED CARBON NANOTUBES | - |
dc.subject.keywordPlus | MAGNETIC TWEEZERS | - |
dc.subject.keywordPlus | LIVING CELLS | - |
dc.subject.keywordPlus | DEFORMABILITY | - |
dc.subject.keywordPlus | ELASTOGRAPHY | - |
dc.subject.keywordPlus | FEASIBILITY | - |
dc.citation.endPage | 22 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 11 | - |
dc.citation.title | Biomedical Optics Express | - |
dc.citation.volume | 6 | - |