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dc.contributor.author Hwang, Jae Youn -
dc.contributor.author Kang, Bong Jin -
dc.contributor.author Lee, Changyang -
dc.contributor.author Kim, Hyung Ham -
dc.contributor.author Park, Jinhyoung -
dc.contributor.author Zhou, Qifa -
dc.contributor.author Shung, K. Kirk -
dc.date.available 2017-07-11T06:01:20Z -
dc.date.created 2017-04-10 -
dc.date.issued 2015-01 -
dc.identifier.issn 2156-7085 -
dc.identifier.uri http://hdl.handle.net/20.500.11750/2944 -
dc.description.abstract We demonstrate a novel non-contact method: acoustic radiation force impulse microscopy via photoacoustic detection (PA-ARFI), capable of probing cell mechanics. A 30 MHz lithium niobate ultrasound transducer is utilized for both detection of phatoacoustic signals and generation of acoustic radiation force. To track cell membrane displacements by acoustic radiation force, functionalized single-walled carbon nanotubes are attached to cell membrane. Using the developed microscopy evaluated with agar phantoms, the mechanics of highly- and weakly-metastatic breast cancer cells are quantified. These results clearly show that the PA-ARFI microscopy may serve as a novel tool to probe mechanics of single breast cancer cells. © 2014 Optical Society of America. -
dc.publisher OSA - The Optical Society -
dc.title Non-contact acoustic radiation force impulse microscopy via photoacoustic detection for probing breast cancer cell mechanics -
dc.type Article -
dc.identifier.doi 10.1364/BOE.6.000011 -
dc.identifier.scopusid 2-s2.0-84942373495 -
dc.identifier.bibliographicCitation Biomedical Optics Express, v.6, no.1, pp.11 - 22 -
dc.description.isOpenAccess FALSE -
dc.subject.keywordPlus FUNCTIONALIZED CARBON NANOTUBES -
dc.subject.keywordPlus MAGNETIC TWEEZERS -
dc.subject.keywordPlus LIVING CELLS -
dc.subject.keywordPlus DEFORMABILITY -
dc.subject.keywordPlus ELASTOGRAPHY -
dc.subject.keywordPlus FEASIBILITY -
dc.citation.endPage 22 -
dc.citation.number 1 -
dc.citation.startPage 11 -
dc.citation.title Biomedical Optics Express -
dc.citation.volume 6 -

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