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A Quantitative Electroencephalography Study on Cochlear Implant-Induced Cortical Changes in Single-Sided Deafness with Tinnitus

A Quantitative Electroencephalography Study on Cochlear Implant-Induced Cortical Changes in Single-Sided Deafness with Tinnitus
Song, Jae-JinKim, KyungsooSunwoo, WoongsangMertens, GrietVan de Heyning, PaulDe Ridder, DirkVanneste, SvenLee, Sang-YoupPark, Kyung-JoonChoi, HongsooChoi, Ji-Woong
DGIST Authors
Kim, Kyungsoo; Park, Kyung-JoonChoi, HongsooChoi, Ji-Woong
Issue Date
Frontiers in Human Neuroscience, 11
Article Type
Auditory CortexBrainCochlear ImplantationCochlear ImplantationDefault ModeDistressDynamic Peripheral ReafferentationDynamic Peripheral ReafferentationElectroencephalographyElectroencephalographyLate Onset TinnitusOrbitofrontal CortexPlasticitySingle Side DeafnessSingle Side DeafnessSuppressionTinnitusTinnitusUnilateral DeafnessVegetative State
The mechanism of tinnitus suppression after cochlear implantation (CI) in single-sided deafness (SSD) is not fully understood. In this regard, by comparing pre- and post-CI quantitative electroencephalography (qEEG), we explored cortical changes relevant to tinnitus improvement. In SSD patients who underwent CI, qEEG data were collected: (1) before CI, (2) 6 months post-operatively with CI-on, and (3) 30 min after CI-off and source-localized cortical activity/functional connectivity analyses were performed. Compared to the pre-operative baseline, the CI-on condition demonstrated significantly decreased activity in the right auditory- and orbitofrontal cortices (OFC) for the delta frequency band as well as decreased connectivity between the auditory cortex/posterior cingulate cortex for the delta/beta2 bands. Meanwhile, compared to the CI-off condition, the CI-on condition displayed decreased activity in the right auditory cortices/OFC for the delta band, and in bilateral auditory cortices, left inferior frontal cortex/OFC for the gamma band. However, qEEG analyses showed no significant differences between the CI-off and baseline conditions. CI induced overall decreased cortical activity and functional connectivity. However, judging from no differences between the CI-off and baseline conditions, CI-induced cortical activity and functional connectivity changes are not by cortical plastic changes, but by dynamic peripheral reafferentation. © 2017 Song, Kim, Sunwoo, Mertens, Van de Heyning, De Ridder, Vanneste, Lee, Park, Choi and Choi.
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Related Researcher
  • Author Choi, Hong Soo Bio-Micro Robotics Lab
  • Research Interests Micro/Nano robot; Neural prostheses; MEMS; BMI; MEMS/NEMS; BioMEMS; MEMS 초음파 트랜스듀스; 인공와우
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Information and Communication EngineeringCSI(Cyber-Physical Systems Integration) Lab1. Journal Articles
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