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Application of Functional Near-Infrared Spectroscopy to the Study of Brain Function in Humans and Animal Models

Title
Application of Functional Near-Infrared Spectroscopy to the Study of Brain Function in Humans and Animal Models
Authors
Kim, Hak-YeongSeo, KainJeon, Hong-JinLee, Un-JooLee, Hyo-Sang
DGIST Authors
Kim, Hak-Yeong; Seo, Kain; Lee, Hyo-Sang
Issue Date
2017
Citation
Molecules and Cells, 40(8), 523-532
Type
Article
Article Type
Review
Keywords
Attention-Deficit/Hyperactivity DisorderAutism Spectrum DisorderBlood Oxygenation ChangesBrain RecordingDeficit Hyperactivity DisorderfNIRSFunctional Near-Infrared SpectroscopyFunctional NeuroimagingHemodynamic-ResponseIn-vivoMajor Depressive DisorderNeurovascular CouplingPrefrontal CortexVerbal Fluency TaskWorking-Memory
ISSN
1016-8478
Abstract
Functional near-infrared spectroscopy (fNIRS) is a noninvasive optical imaging technique that indirectly assesses neuronal activity by measuring changes in oxygenated and deoxygenated hemoglobin in tissues using near-infrared light. fNIRS has been used not only to investigate cortical activity in healthy human subjects and animals but also to reveal abnormalities in brain function in patients suffering from neurological and psychiatric disorders and in animals that exhibit disease conditions. Because of its safety, quietness, resistance to motion artifacts, and portability, fNIRS has become a tool to complement conventional imaging techniques in measuring hemodynamic responses while a subject performs diverse cognitive and behavioral tasks in test settings that are more ecologically relevant and involve social interaction. In this review, we introduce the basic principles of fNIRS and discuss the application of this technique in human and animal studies. © The Korean Society for Molecular and Cellular Biology. All rights reserved.
URI
http://hdl.handle.net/20.500.11750/4569
DOI
10.14348/molcells.2017.0153
Publisher
Korean Society for Molecular and Cellular Biology
Related Researcher
  • Author Lee, Hyo Sang Laboratory of Affective Neuroscience
  • Research Interests Neuronal circuit mechanisms underlying emotional behaviors; 정서적 행동을 매개하는 신경회로 연구
Files:
There are no files associated with this item.
Collection:
Brain and Cognitive SciencesLaboratory of Affective Neuroscience1. Journal Articles


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