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MEMS-based Microelectrode Technologies Capable of Penetrating Neural Tissues
- MEMS-based Microelectrode Technologies Capable of Penetrating Neural Tissues
- 추남선; 변동학; 김소희
- DGIST Authors
- Issue Date
- Biomedical Engineering Letters (BMEL), 4(2), 109-119
- Penetrating electrode; Neural electrode; Microelectrode; Silicon-based; Polymer-based; MEMS
- Due to the high spatial selectivity and resolution with highaccessibility to single neurons, penetrating neural electrodeshave been used for neuronal recording or stimulation inspecific applications although they are invasive, thus inducingmore inflammatory response and damages to the tissue,compared to non-penetrating electrodes. Penetrating electrodesare mainly made up of stiff materials such as metal wires,silicon, or glass. Compared to microwire electrodes, siliconbasedpenetrating electrodes are fabricated in precise designsand dimensions, often in forms of array with higher numberof independent channels. Although precise 2-D and 3-Delectrode structures are used in many applications, efforts tomake them more biocompatible and long-lasting have beenreported recently. On the other hand, soft materials such aspolymers have also been lately used in penetrating electrodesto accommodate their flexibility and mechanical propertiesthat are more favorable to neural tissues, minimizing adverseeffects on tissues. Polymer-based electrodes are promisingfor future applications where better biocompatibility isrequired although technical hurdles in using them in longterm have to be overcome.
- Related Researcher
Kim, So Hee
Neural Interfaces & MicroSystems Lab
Neural interface; Neural stimulation; Bio MEMS; Stretchable electronics; Numerical simulation of implant-body interactions
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