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Stereocontrolled Synthesis of the C1-C10 Fragments of Monensin B and Laidlomycin

Title
Stereocontrolled Synthesis of the C1-C10 Fragments of Monensin B and Laidlomycin
Authors
Kang, SungkyoungLee, WonchulJung, ByunghyuckLee, Hee-SeungKang, Sung Ho
DGIST Authors
Jung, Byunghyuck
Issue Date
2015-06
Citation
Asian Journal of Organic Chemistry, 4(6), 567-572
Type
Article
Article Type
Article
Keywords
Aldol ReactionLaidlomycinMonensinbTishchenko-Evans ReactionTotal Synthesis
ISSN
2193-5807
Abstract
An efficient synthetic route to the C1-C10 fragments of laidlomycin and monensin B has been developed toward their total synthesis. The asymmetric carbons have been elaborated by a syn-aldol reaction using the oxazolidinone chiral auxiliary for C6 and C7, an anti-aldol reaction for C3 and C4, the Tishchenko-Evans reaction for C5, and a chiral building block for C2. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
URI
http://hdl.handle.net/20.500.11750/5186
DOI
10.1002/ajoc.201500078
Publisher
Wiley-VCH Verlag
Related Researcher
Files:
There are no files associated with this item.
Collection:
School of Undergraduate Studies1. Journal Articles


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