Repository Collection: nullhttps://scholar.dgist.ac.kr/handle/20.500.11750/100392026-04-04T15:18:28Z2026-04-04T15:18:28Z혀 오가노이드의 제조방법 및 이의 용도정영태오병무명지현https://scholar.dgist.ac.kr/handle/20.500.11750/601442026-02-28T17:10:20ZTitle: 혀 오가노이드의 제조방법 및 이의 용도
Author(s): 정영태; 오병무; 명지현
Abstract: 혀 오가노이드의 제조방법 및 이의 용도에 관한 것으로 혀의 중층편평상피(stratified squamous epithelium)을 재현하는 혀 오가노이드 제조용 배지 및 제조 방법을 제공하며, 이를 활용하여 혀 오가노이드의 장기 계대배양을 가능케 하며, 약물 처리 플랫폼으로 활용한다.METHOD FOR PRODUCING MULTI-TISSUE LUNG ORGANOID SURROUNDED BY FIBROBLASTS, AND USE THEREOF명지현김클스틴슬기정영태https://scholar.dgist.ac.kr/handle/20.500.11750/598932026-01-29T16:10:17ZTitle: METHOD FOR PRODUCING MULTI-TISSUE LUNG ORGANOID SURROUNDED BY FIBROBLASTS, AND USE THEREOF
Author(s): 명지현; 김클스틴슬기; 정영태
Abstract: The present invention relates to a method for producing a multi-tissue lung organoid structurally surrounded by fibroblasts, and a use thereof, and provides a three-dimensional structure composed of a lung organoid and a fibroblast layer surrounding the outside thereof. The organoid according to the present invention can maintain a high level of structural stability and bio-fidelity by reproducing a cell arrangement and microenvironment similar to those of actual lung tissue. The multi-tissue organoid more precisely reproduces a microenvironment in which epithelial tissues and interstitial tissues are arranged in layers as in a living body, rather than adopting a simple cell mixing method, and thus can be used in various biomedical applications, such as regenerative medicine, research on lung disease conditions, and evaluation of responsiveness to anticancer drugs and anti-fibrotic drugs. In addition, the present invention has excellent expandability to organoid-on-chip technology or bio-artificial organ development, and thus can be expected to be used as a precision medicine and next-generation cell therapy platform.자궁경부 오가노이드의 제조방법 및 이의 용도이바울정영태https://scholar.dgist.ac.kr/handle/20.500.11750/592992025-12-31T17:10:16ZTitle: 자궁경부 오가노이드의 제조방법 및 이의 용도
Author(s): 이바울; 정영태
Abstract: 본 발명은 자궁경부 오가노이드의 제조방법 및 이의 용도에 관한 것으로 자궁경부의 중층편평상피 (stratified squamous epithelium) 을 재현하는 자궁경부 오가노이드 제조용 배지 및 제조 방법을 제공하며, 이를 활용하여 자궁경부 오가노이드의 장기 계대배양을 가능케 하며, 약물 처리 플랫폼으로 활용할 수 있다.