https://scholar.dgist.ac.kr/handle/20.500.11750/13572 2026-06-04T00:54:33Z https://scholar.dgist.ac.kr/handle/20.500.11750/60379 Title: 수치적분 기반의 확산 상관 분광법 Author(s): 김재관; 오윤호; 이기준 Abstract: 본 발명은 광신호에 곧바로 수치적분을 적용함으로써, 물리적 모델에 대한 데이터 피팅 없이도 혈류 변화를 실시간으로 측정할 수 있는 확산 상관 분광법에 관한 것이다. 본 발명의 일 실시예에 따른 수치적분 기반의 확산 상관 분광법은 조직에서 산란된 레이저의 광신호를 획득하는 단계, 상기 광신호에 기초하여 필드 자기상관 함수를 산출하는 단계 및 상기 필드 자기상관 함수에 수치적분을 적용하여 상기 조직 내 혈관에 대한 혈류 인덱스를 결정하는 단계를 포함하는 것을 특징으로 한다. https://scholar.dgist.ac.kr/handle/20.500.11750/60245 Title: 지정위치에서 지구 모습을 상상할 수 있는 지구모델 Author(s): 이기준 https://scholar.dgist.ac.kr/handle/20.500.11750/60223 Title: Local Microcirculation Level Changes During Laser Acupuncture Treatment of Rats With Osteoarthritis Author(s): Park, Jae Yoon; Youn, Cha-kyung; Kang, Sang-mi; Choi, Gisoon; Jang, Seo Won; Chung, Hea Ik; Kim, Jae-min; Myeong, Ju-yeong; Yang, Ji-hye; Nguyen, Cong Duc; You, Yanghee; Na, Changsu; Lee, Kijoon Abstract: This study evaluates whether a deep-tissue microcirculation measurement can serve as an indicator of laser acupuncture treatment efficacy in an osteoarthritis (OA) animal model. Four groups of rats (normal, OA, OA10, and OA20, n = 6 each) were prepared where OA10 and OA20 mean treated groups with different light doses. Blood flow index (BFI) was measured at four time points (T0–T3) near acupoints GB34 and GB39 using a custom-made diffuse speckle contrast analysis (DSCA) system. BFI measurement showed an increase after OA induction and it remained elevated, whereas treatment groups exhibited a decrease in BFI. Spectral analysis revealed meaningful changes in the myogenic wave band, and a support vector machine classification demonstrated that incorporating BFI at T1 along with anatomical features significantly improved group separation accuracy, indicating a strong correlation between acute inflammatory response and anatomical indices. 2025-12-31T15:00:00Z https://scholar.dgist.ac.kr/handle/20.500.11750/59974 Title: Diffuse speckle contrast analysis for flowmetry with deep light sources Author(s): Jang, Seo Won; Moon, Soomin; Park, Jae Yoon; Lee, Tae Gyun; Lee, Kijoon Abstract: Diffuse optical probes for monitoring various hemodynamic variables usually use tissue-contacting fiber based probes, and no practical cases exist where source location is positioned in deep tissue, as diffuse optical spectroscopy and tomography are normally regarded as a non-invasive imaging technique. There are some cases, however, where the light source is positioned in deep tissue, as in the case of recently developed laser acupuncture. In this study, we theoretically analyze the light propagation in a semi-infinite diffuse medium with a deep light source, especially in the context of blood flow measurement. A liquid phantom study with deep light sources is performed to validate the analytic solution of photon diffusion equation, and a diffuse speckle contrast analysis (DSCA) measurement from a flow phantom within a solid matrix is performed to demonstrate the feasibility of the proposed method. The results show that the flow measurement using DSCA with a deep light source is not only feasible, but also has advantages in some cases. Sensitivity analysis shows the light source with a depth of up to 2 cm can be used to provide the information on the magnitude and location of blood flow. 2026-02-28T15:00:00Z