https://scholar.dgist.ac.kr/handle/20.500.11750/10164 Sun, 15 Nov 2026 15:11:43 GMT 2026-11-15T15:11:43Z https://scholar.dgist.ac.kr/handle/20.500.11750/61114 Title: Third-Harmonic Generation in Crumpled Silicon Nanomembranes Author(s): Lee, Gwanjin; Katiyar, Ajit K.; Ahn, Jong-Hyun; Kim, Hyunmin; Lee, JaeDong Abstract: Silicon nanomembranes provide mechanically compliant devices for strain engineering. Here, we investigate third-harmonic generation in flat and crumpled silicon nanomembranes of 15 and 35 nm using polarization-resolved third-harmonic generation microscopy with ab initio calculations. In flat silicon nanomembranes, the measured polarization dependence is reproduced by the calculated third-order susceptibility, identifying the intrinsic nonlinear response of silicon. In crumpled silicon nanomembranes, local strain variations between valleys and apexes generate distinct polarization-dependent responses. Uniaxial strain along the [110] direction breaks electronic structure symmetry and induces anisotropy between X- and Y-polarized components, while the real and imaginary parts of the third-order susceptibility exhibit quadratic strain dependence. Morphology-induced redistribution of the local optical field further modifies the response in crumpled geometry, and a finite-difference time-domain-based local-field correction substantially improves agreement with the experiment. Therefore, the third-harmonic response of crumpled silicon nanomembranes is controlled by both strain-induced electronic structure modification and morphology-induced local optical-field redistribution. Wed, 30 Sep 2026 15:00:00 GMT https://scholar.dgist.ac.kr/handle/20.500.11750/61114 2026-09-30T15:00:00Z https://scholar.dgist.ac.kr/handle/20.500.11750/61097 Title: Multi-modality image fusion model of AFM-derived extracellular vesicles for NSCLC subtype diagnosis Author(s): Kim, Haeyoung; 박수현; Lee, Yoonhee; Ban, Jaepil; Koo, Gyogwon Abstract: Non-small cell lung cancer (NSCLC) comprises multiple subtypes with distinct treatment strategies, making accurate subtype classification important. Therefore, this study aims to develop a multi-modality AFM-based deep learning model to improve NSCLC subtype diagnosis because extracellular vesicles (EVs) measured by atomic force microscopy (AFM) contain nanoscale biophysical information with diagnostic potential. The proposed model introduces two key components: (i) an intra-image feature extractor (IFE), which captures parameter-specific local and global dependencies, and (ii) a cross-image feature fusion module (CFFM), which mitigates domain mismatch among heterogeneous AFM parameters. Through three fusion strategies at the image, low-level feature, and high-level feature stages, the proposed model simultaneously learns intraparameter and inter-parameter relationships. The proposed model achieved an accuracy of 0.9245 and an area under the receiver operating characteristic curve (AUROC) of 0.9804, outperforming the AFM-based conventional state-of-the-art (SOTA) model by improvements of 0.1328 in accuracy and 0.0273 in AUROC. These results demonstrate that the proposed multi-modality fusion approach achieves superior diagnostic performance for AFM-based EV analysis. Furthermore, the proposed framework has the potential to be extended to AFM-based analysis of other cell types and diseases once large-scale datasets are secured. Code is released at https://github.com/sunh124/MMIF_Model_of_AFM-derived_EV. Wed, 30 Sep 2026 15:00:00 GMT https://scholar.dgist.ac.kr/handle/20.500.11750/61097 2026-09-30T15:00:00Z https://scholar.dgist.ac.kr/handle/20.500.11750/60897 Title: A Steerable and Expandable Magnetic Aspiration Catheter for Enhanced Aspiration Thrombectomy Author(s): Lee, Hakjoon; Dong Xiao; Kim, Dong-in; Chowdhury, A. M. Masum Bulbul; Gharamaleki, Nader Latifi; Kim, Jin-young; Youn, Sung Won; Choi, Hongsoo Abstract: Aspiration thrombectomy is widely used when treating acute ischemic stroke. A blood clot is directly suctioned through a catheter connected to a vacuum system. Although an increase in catheter bore size significantly enhances aspiration efficiency, this compromises endovascular navigability during manual manipulation. To minimize this trade-off, this paper presents a novel, magnetic aspiration catheter that enables both active steering and distal-end expansion via externally applied magnetic fields. The catheter incorporates dual-axis magnetization. Axial magnetization facilitates directional steering by aligning the catheter tip with the magnetic field; radial magnetization enables dynamic expansion of the cross-sectional area in response to the field strength, thereby improving clot contact and reducing leakage between the catheter and vessel wall. A magnetic mold-based fabrication method is employed to realize such dual-axis magnetization. The magnetically actuated motions of the catheter are theoretically and experimentally validated. Active steering reduces the navigation time by 67.5% (30.3 vs. 93.1 s) and expansion increases the aspiration force by 430% (27 vs. 143 & micro;N). Catheter efficacy and feasibility in terms of aspiration thrombectomy are demonstrated using 3D vascular phantoms. By enhancing both navigational control and therapeutic performance, this study advances the development of practical robotic systems for rapid and precise stroke treatment. Tue, 30 Jun 2026 15:00:00 GMT https://scholar.dgist.ac.kr/handle/20.500.11750/60897 2026-06-30T15:00:00Z https://scholar.dgist.ac.kr/handle/20.500.11750/60879 Title: Magnetic Control of Intravascular Collaborative Robotic (Cobot) Guidewire: Neurovascular Intervention Studies in Phantom and Swine Models Author(s): Kim, Dong-in; Kim, Beomjoo; Lee, Hakjoon; Hwang, Junsun; Jeon, Sungwoong; Kim, Jin-young; Youn, Sung Won; Choi, Hongsoo Abstract: Strokes such as acute ischemic stroke require vascular access for endovascular thrombectomy. To navigate the small and complex cerebral vessels with multiple branches, clinicians use guidewires or catheters with pre-shaped tips. However, complex procedures still face the problem of increased X-ray exposure for both clinicians and patients. Engineering technologies such as robotic guidewires and catheters are being applied to neurovascular procedures to make them faster and more effective. The technology presented in this study involves Collaborative Robotic (Cobot) guidewires that can be steered by magnetic fields to effectively enter the target vessel and navigate complex blood vessels. The Cobot guidewire can be steered according to the direction of the magnetic field because its tip contains a permanent magnet and a magnetic polymer. The magnetic field for steering the Cobot guidewire can be controlled and generated by electromagnetic control systems (ECS). In this study, the performance of neurovascular procedures using the Cobot guidewire and manual guidewire is compared in both phantom and swine models. Based on various parameters, the Cobot guidewire demonstrates superior performance in neurovascular procedures compared to the manual guidewire. Favorable procedure time and navigation efficiency suggest that a magnetically assisted Cobot guidewire is potentially feasible for neurovascular interventions. Tue, 30 Jun 2026 15:00:00 GMT https://scholar.dgist.ac.kr/handle/20.500.11750/60879 2026-06-30T15:00:00Z