https://scholar.dgist.ac.kr/handle/20.500.11750/1200 Sat, 04 Apr 2026 15:51:15 GMT 2026-04-04T15:51:15Z https://scholar.dgist.ac.kr/handle/20.500.11750/57812 Title: Magnetically Actuated Capsule with Multiple Sampling Capability for Gut Microbiome Research Author(s): Park, Sanghyeon; Park, Sukho Abstract: Understanding the relationship between gut microbiota and gastrointestinal (GI) diseases through longitudinal analysis is vital for advancing diagnosis and treatment methods. To achieve this, ingestible devices capable of multipoint gut microbiota sampling are necessary. Conventional devices move passively through the GI tract, relying on physiological factors and are unable to perform multipoint sampling. This study introduces a novel magnetically actuated capsule robot designed to collect gut microbiota from various GI tract locations while minimizing cross-contamination. The capsule includes a body, a driving unit, six sampling tools, a central rod, and two heads. It uses electromagnetic field control for precise orientation and position of the capsule, ensuring the sampling channel faces downward for accurate collection. The capsule can collect six distinct microbiota samples, protecting the tools from contamination throughout the process. Its active locomotion and sampling capabilities were tested through ex-vivo tests. The feasibility of clinical application was demonstrated in preclinical trials using a porcine model, confirming the capsule's potential for integration and use in medical settings. © 2024 ICROS. Tue, 29 Oct 2024 15:00:00 GMT https://scholar.dgist.ac.kr/handle/20.500.11750/57812 2024-10-29T15:00:00Z https://scholar.dgist.ac.kr/handle/20.500.11750/56790 Title: 향상된 감각 피드백을 위한 공압-자기 통합형 햅틱 장치 Author(s): 기초학부 비전임; 박주원; 박석호 Abstract: Transmitting haptic patterns accurately and realistically is an important characteristic in the development of haptic devices. However, when touching a real object, there are high-frequency sensory patterns such as surface pattern or texture and low-frequency sensory patterns such as weight or shape, so there is a limit to transmitting sensory signals with one actuator. In this paper, we propose a Pneumatic-Magnetic integrated module for realistic sensory transmission. The low-frequency component of an arbitrary sensory pattern was implemented using a pneumatic actuator, and the high-frequency component was implemented using a magnetic actuator by following their mechanical characteristics. Several Experiments were conducted to prove the mechanical property of the proposed haptic device. In conclusion, the proposed haptic device is expected to transmit haptic patterns more accurately and realistically. Tue, 20 Jun 2023 15:00:00 GMT https://scholar.dgist.ac.kr/handle/20.500.11750/56790 2023-06-20T15:00:00Z https://scholar.dgist.ac.kr/handle/20.500.11750/56789 Title: 능동 전달 및 약물 방출을 위한 점막 접착 패치 개발 Author(s): 이지훈; 박석호 Abstract: Drug delivery in the gastrointestinal tract has been variously studied, and improving drug delivery efficiency is an important issue. In this paper, we propose a drug-loaded mucoadhesive patch capable of active delivery and drug release promotion. The proposed mucoadhesive patch has excellent adhesion even in the wet intestinal environment and is capable of hyperthermia and drug release promotion. The proposed patch is mounted in our wireless capsule with open-close mechanism and can be actively delivered to two or more lesions. The possibility of patch delivery to the gastrointestinal tract was verified through an ex-vivo test using porcine small intestine. In addition, cytotoxicity experiments using HT-29 cells were performed to confirm the cancer cell-killing. Tue, 20 Jun 2023 15:00:00 GMT https://scholar.dgist.ac.kr/handle/20.500.11750/56789 2023-06-20T15:00:00Z https://scholar.dgist.ac.kr/handle/20.500.11750/56784 Title: 재구성 및 적응형 구동을 위한 온도 반응형 자기 섬모 Author(s): 기초학부 비전임; 손선우; 박석호 Abstract: In this study, we report on the design, fabrication, and characterization of temperature-triggered magnetic cilia for reconfigurable and adaptive actuation. The temperature-responsive magnetic cilia are composed of magnetic cobalt nanoparticles that are coated by oleic acid to increase their dispersion which can be actuated by an external magnetic field to induce bending and twisting motions. Also, it includes temperature-responsive wax materials including paraffin wax and paraffin liquid that allow for dynamic control of the cilia's stiffness and shape. By modulating the temperature of the surrounding environment, we demonstrate that our cilia can exhibit a wide range of behaviors, including spontaneous reconfiguration, directional motion, and self-adaptation to complex environments. Also, according to the substance of the surface, the behavior of the cilia liquid could be controlled. Our approach represents a promising strategy for the development of microscale devices with enhanced functionality and versatility, and has potential applications in fields such as biomedical engineering, environmental monitoring, and microfluidics. Wed, 21 Jun 2023 15:00:00 GMT https://scholar.dgist.ac.kr/handle/20.500.11750/56784 2023-06-21T15:00:00Z