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Optically Transparent Focused Transducers for Combined Photoacoustic and Ultrasound Microscopy
- Optically Transparent Focused Transducers for Combined Photoacoustic and Ultrasound Microscopy
- Park, Sunghun; Kang, Sungwoo; Chang, Jin Ho
- DGIST Authors
- Chang, Jin Ho
- Issue Date
- Journal of Medical and Biological Engineering
- Article Type
- Article in press
- Author Keywords
- Optically transparent sensor; Photoacoustic signal detection; Photoacoustic microscopy; Ultrasound imaging; Hybrid imaging
- HIGH-FREQUENCY; ELEMENT TRANSDUCERS; HIGH-RESOLUTION; DESIGN; FABRICATION; SENSITIVITY
- Purpose: Photoacoustic (PA) microscopy has emerged as a useful tool in biomedical imaging applications such as visualization of microvasculature and hemoglobin oxygen saturation, single-cell, and label-free imaging of organs including cancer. Since the ultrasound transducers used for PA signal detection are not optically transparent, the integration of optical and acoustic modules for coaxial alignment of laser and acoustic beam fields in PA microscopy is complex and costly. Methods: Here, we report a recently developed optically transparent focused transducer for combined PA and ultrasound (US) microscopy. All the acoustic layers including the acoustic lens are optically transparent, enabling simple integration of optical and acoustic modules for both imaging modalities. Results: The mean light transmittance of the transducer’s backing layer and acoustic lens and of the transducer itself were measured at 92%, 83%, and 66%, respectively. Results from in vitro and in vivo experiments demonstrated the transducer to be suitable for both US and PA imaging. Conclusions: The results of this study represent a step toward efficient construction of probes for combined PA and US microscopy. © 2020, The Author(s).
- Related Researcher
Chang, Jin Ho
Medical Acoustic Fusion Innovation Lab.
Biomedical Imaging, Signal and Image Processing, Ultrasound Imaging System, Ultrasound Transducer, Photoacoustic Imaging
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- Department of Information and Communication EngineeringMedical Acoustic Fusion Innovation Lab.1. Journal Articles
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