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Comparing the difference in expression of exosomal biomarkers between exosomes from serum and tissue in cancer patients

Title
Comparing the difference in expression of exosomal biomarkers between exosomes from serum and tissue in cancer patients
Authors
Kim, Jung-HeeKim, EunjooEun-sook, ChoiFaruque, Md Hasan Al
DGIST Authors
Kim, Jung-Hee; Kim, Eunjoo
Issue Date
2019-10-31
Citation
2019 한국공업화학회 추계 총회 및 학술대회
Type
Conference
Abstract
Exosomes, nano-sized extracellular vesicles, are reported to harbor signaling molecules to communicate between remote cells. Due to this reason, exosomal biomarkers have received interests as a source of early detection of cancers. To determine whether the exosomes affect tumor progression in cancer patients, we primarily identified the changes in exosomal protein contents exosomes from serum in cancer patient. We select the best exosomal biomarkers from exosomes in cancer patients. In this study, we compared the expression level of exosomal biomarkers in serum exosomes of cancer patients vs. tissue of cancer patients. Exosomal biomarkers were detected at higher levels in serum exosome from cancer patients compared to tissue. These results suggest that increased exosomal biomarkers from serum exosomes in cancer patients is associated with cancer progression.
URI
http://hdl.handle.net/20.500.11750/14209
Publisher
한국공업화학회
Related Researcher
  • Author Kim, Eunjoo  
  • Research Interests Biomarker, liquid biopsy, molecular diagnosis, nanobiosensor, drug delivery, exosome
Files:
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Collection:
Division of Electronics & Information System2. Conference Papers


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