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Development of a Portable Optical Imaging System based on a Smartphone and Image Classification using a Learning Algorithm

Development of a Portable Optical Imaging System based on a Smartphone and Image Classification using a Learning Algorithm
Translated Title
모바일 기반의 소형 다중 분광 이미징 시스템 개발을 통한 지루성 피부염 및 건선 구별
Kim, Man Jae
DGIST Authors
Lee, Ki Joon; Kim, Man Jae; Hwang, Jae Youn
Hwang, Jae Youn
Lee, Ki Joon
Issue Date
Available Date
Degree Date
2017. 2
Multispectral ImagingSeborrheic DermatitisPsoriasisLogistic RegressionMobile Healthcare분광 이미징스마트폰지루성피부염건선
To date, various skin diseases have incrementally increases due to hereditary and environmental factors including the stress, irregular diet, pollution, and etc. Among diseases, seborrheic dermatitis and psoriasis are a chronic/relapsing dermatitis, which involve infection, temporary alopecia, and etc. To prevent complications and take appropriate prescription due to the diseases, it would be crucial to differentiate seborrheic dermatitis from psoriasis with high specificity and accuracy at the early stages as well as it would further necessary to continuously/quantitatively monitor the lesions during its treatment at locations besides a hospital. However, the discrimination between the diseases at the early stages would be challenging. Optical imaging techniques have been shown to have a crucial role to detect various skin diseases. Among them, an advanced dermoscope based on multispectral imaging techniques offers better specificity and sensitivity in the detection of skin lesions than a conventional RGB dermoscope. However, the advanced dermoscope utilized in the hospital is typically bulk and expensive and thus may not be suited for ubiquitous diagnosis and monitoring of skin lesions including seborrheic dermatitis and psoriasis. In this thesis, we here demonstrate a portable mobile multispectral imaging system attached to a smartphone with an external C-MOS camera and the potential learning-based classification method for detection of seborrheic dermatitis and psoriasis by using it. The system allowed to obtain images of skin lesions at nine consecutive wavelengths within the range of 400-700nm. It was here employed to perform multispectral imaging and analysis of lesions to discriminate between seborrheic dermatitis and psoriasis or other diseased regions. Also, the results classified by a RGB image classification, a spectral angle measure (SAM), and a multiclass classification method based on a learning algorithm were compared. It was here found that spectral signatures of seborrheic dermatitis and psoriasis were slightly different but they could be clearly discernable by their spectral signatures. The SAM and multiclass classification method offered better accuracy in discrimination between of seborrheic dermatitis and psoriasis occurring on the scalp than the RGB image classification method. These results suggested that the multispectral imaging and learning-based analysis may have the potential to discriminate between seborrheic dermatitis and psoriasis regions with high portability and acceptable specificity for mobile skin diagnosis. ⓒ 2017 DGIST
Table Of Contents
I. Introduction 1-- 1.1 Seborrheic Dermatitis and Psoriasis 1-- 1.2 Multispectral Imaging 3 -- 1.3 Background 6 -- 1.4 Related Works 14 -- 1.5 Goal of this Thesis 17 -- II. Methods 18 -- 2.1 Development of a Smartphone-based Multispectral Imaging System for Selfdiagnosis 18 -- 2.2 System Validation by using the LCTF and Another Optical Components 31 -- 2.3 Spectral Analysis of Image Cube of Seborrheic Dermatitis and Psoriasis 34 -- 2.4 One-VS-all Logistic regression for Classification of Seborrheic Dermatitis, Psoriasis, and Normal Regions 35-- III. Results 36 -- 3.1 Analysis of Spectral signatures of Seborrheic Dermatitis and Psoriasis 36 -- 3.2 Spectral classification using Multiclass Classification based on One-VS-All Algorithm and SAM (spectral angle measurement) 38-- IV. Discussions 40 -- V. Conclusions 43-- VI. Appendix 44-- VII. References 45
Information and Communication Engineering
Information and Communication EngineeringThesesMaster

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