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Hydroxamate Transfer and Oxidative Reactivity of Cobalt and Iron Complexes in Biomimetic Model Chemistry

Title
Hydroxamate Transfer and Oxidative Reactivity of Cobalt and Iron Complexes in Biomimetic Model Chemistry
Alternative Title
생체 모방화학을 활용한 코발트와 철 착물의 하이드록사메이트 전달과 산화반응성
Author(s)
Nam Kwon
DGIST Authors
Nam KwonNak Cheon JeongJaeheung Cho
Advisor
정낙천
Co-Advisor(s)
Jaeheung Cho
Issued Date
2021
Awarded Date
2021/02
Type
Thesis
Subject
Metalloenzyme, Biomimetic chemistry, Cobalt prodrug, Drug delivery mechanism, Reactive diiron-dioxygen complex, Amphoteric reactivity, 금속 효소, 생체 모방 화학, 코발트 프로드러그, 약물 전달반응, 이핵 철 이산소 화합물, 양쪽성 반응
Table Of Contents
General Introduction 1
Chapter 1. Mechanistic Insight into Hydroxamate Transfer Reaction Mimicking the Inhibition of Zinc-Containing Enzymes 16
1.1. Abstract. 16
1.2. Introduction 18
1.3. Results and Discussion. 20
1.4. Conclusion. 48
1.5. Experimental Section 49
1.6. References 58
Chapter 2. Amphoteric Reactivity in Nucleophilic and Electrophilic Oxidation of Diiron Peroxo Complex 63
2.1. Abstract 63
2.2. Introduction 64
2.3. Results and Discussion. 66
2.4. Conclusion 71
2.5. Experimental Section 72
2.6. References 74
Concluding Remarks 78
Acknowledgement 80
URI
http://dgist.dcollection.net/common/orgView/200000361891

http://hdl.handle.net/20.500.11750/16648
DOI
10.22677/thesis.200000361891
Degree
Doctor
Department
Emerging Materials Science
Publisher
DGIST
Related Researcher
  • 정낙천 Jeong, Nak Cheon
  • Research Interests Inorganic Chemistry; Metal-Organic Framework; Nanoporous Materials; Electron Transport;Ion Transport
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Department of Physics and Chemistry Theses Ph.D.

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