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dc.contributor.advisor 최홍수 -
dc.contributor.author Sungwoong Jeon -
dc.date.accessioned 2022-07-07T02:29:10Z -
dc.date.available 2022-07-07T02:29:10Z -
dc.date.issued 2021 -
dc.identifier.uri http://dgist.dcollection.net/common/orgView/200000363762 en_US
dc.identifier.uri http://hdl.handle.net/20.500.11750/16681 -
dc.description.statementofresponsibility N -
dc.description.tableofcontents 1. Introduction 1
1.1 Background 1
1.2 Research trends 4
1.2.1 Microrobots for targeted therapy 4
1.2.2 Microrobots for stem cell therapy 8
1.3 Objectives of research 11
2. Magnetically actuated microrobots as a platform for stem cell transplantation 15
2.1 Introduction 15
2.2 Results 18
2.2.1 Fabrication and characterization of the microrobots 18
2.2.2 Hippocampal NSC culture and delivery in vitro 22
2.2.3 Ex vivo manipulation of the microrobots 29
2.2.4 In vivo stem cell transportation using the microrobots 31
2.3 Discussion & conclusion 33
2.4 Materials & method 35
3. Magnetically actuated SiCN-based ceramic microrobot for cell delivery 51
3.1 Introduction 51
3.2 Result & discussion 54
3.3 Conclusion 66
3.4 Materials & methods 67
4. Magnetically powered GelMA-based biodegradable microrobot for localized stem cell delivery 73
4.1 Introduction 73
4.2 Result & discussion 76
4.3 Conclusion 86
4.4 Materials & methods 87
5. Intranasal delivery of a stem cell microrobot bypassing the blood-brain barrier 93
5.1 Introduction 93
5.2 Result & Discussion 96
5.3 Conclusion 109
5.4 Materials & methods 111
6. Conclusions & Future work 119
6.1 Conclusions 119
6.2 Future work 121
6.2.1 Magnetically driven piezoelectric microrobot (mpMR) for cell stimulation 121
6.2.2 Fabrication and characterization of the mpMRs 123
6.2.3 Applications of the mpMRs 124
ACKNOWLEDGMENT 126
PUBLICATION LIST 129
REFERENCE 133
요 약 문 145
APPENDIX 148
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dc.format.extent 153 -
dc.language eng -
dc.publisher DGIST -
dc.subject Microrobot, Magnetic actuation, Stem cell therapy, Targeted therapy, MEMS -
dc.title Development of the magnetically powered untethered microrobots for targeted cell therapy -
dc.title.alternative 최초침습 정밀 세포치료를 위한 자기장 구동형 마이크로로봇 개발 -
dc.type Thesis -
dc.identifier.doi 10.22677/thesis.200000363762 -
dc.description.degree Doctor -
dc.contributor.department Robotics Engineering -
dc.contributor.coadvisor Jin-young Kim -
dc.date.awarded 2021/02 -
dc.publisher.location Daegu -
dc.description.database dCollection -
dc.citation XT.RD 전54 202102 -
dc.contributor.alternativeDepartment 로봇공학전공 -
dc.embargo.liftdate 2026-02-28 -
dc.contributor.affiliatedAuthor Sungwoong Jeon -
dc.contributor.affiliatedAuthor Hongsoo Choi -
dc.contributor.affiliatedAuthor Jin-young Kim -
dc.contributor.alternativeName 전성웅 -
dc.contributor.alternativeName Hongsoo Choi -
dc.contributor.alternativeName 김진영 -
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Department of Robotics and Mechatronics Engineering Theses Ph.D.

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