Lactobacillus reuteri ATG-F4 promotes stress-resilience through 5-HT-related signaling
- Title
- Lactobacillus reuteri ATG-F4 promotes stress-resilience through 5-HT-related signaling
- Alternative Title
- Lactobacills reuteri ATG-F4의 항우울 효과에 대한 행동학적 분석과 세로토닌성 기여에 대한 연구
- Author(s)
- Jiyun Lee
- DGIST Authors
- Jiyun Lee ; Yong-Seok Oh ; Ja Wook Koo
- Advisor
- 오용석
- Co-Advisor(s)
- Ja Wook Koo
- Issued Date
- 2022
- Awarded Date
- 2022/08
- Type
- Thesis
- Description
- depression, chronic unpredictable stress, microbiota-gut-brain axis, Lactobacillus reuteri ATG-F4, serotonin
- Abstract
- Table Of Contents
-
I. INTRODUCTION 1
II. METHODS AND MATERIALS 4
III. RESULTS 12
3.1. Antidepressant-like effect of Lactobacillus reuteri ATG-F4 in CUS-induced depressive-like behaviors 12
3.2. Modulation of caecal microbiota by F4 13
3.3. Effect of F4 on 5-HT and 5-HIAA expression levels in serum and the brain 14
3.4. Effect of F4 on 5-HT receptor mRNA expression in the mPFC 14
IV. DISCUSSION 16
V. REFERENCES 38
요 약 문 45
- URI
-
http://dgist.dcollection.net/common/orgView/200000627111
http://hdl.handle.net/20.500.11750/16767
- Degree
- Master
- Department
- Department of Brain Sciences
- Publisher
- DGIST
- Related Researcher
-
-
Oh, Yong-Seok
- Research Interests Monoaminergic regulation of the CNS and mood;anxiety disorder; 모노아민 (세로토닌; 도파민)에 의한 신경조절과 기분;불안 장애 기전 연구
-
- Files in This Item:
-
There are no files associated with this item.
- Appears in Collections:
- Department of Brain Sciences Theses Master
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.