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Ultrasmall Polyethyleneimine-Gold Nanoparticles with High Stability

Title
Ultrasmall Polyethyleneimine-Gold Nanoparticles with High Stability
Authors
Kim, Eun JungYeum, Jeong HyunGhim, Han DoLee, Se GuenLee, Ga HyunLee, Hyun JuHan, Sang IkChoi, Jin Hyun
DGIST Authors
Lee, Se Guen; Lee, Ga Hyun; Lee, Hyun Ju
Issue Date
2011-03
Citation
Polymer-Korea, 35(2), 161-165
Type
Article
Article Type
Article
ISSN
0379-153X
Abstract
This study is related to the preparation of biocompatible gold nanoparticles (AuNPs) which are stable in aqueous solutions for a long time. Ultrasmall polyethyleneimine (PEI)-capped AuNPs (PEI-AuNPs) with limited agglomeration were prepared in aqueous solutions at room temperature, which were based on the roles of PEI as a reductant and a stabilizer. PEI-AuNPs with an average size of 8-12 nm formed highly stable nanocolloids with an average hydrodynamic cluster size of around 50 nm in aqueous media. At a low concentration of metal precursor hydrogen tetrachloroaurate OM, the particle size was reduced noticeably. The typical peaks of gold were observed in the X-ray diffraction pattern of AuNPs. The cell viability of 98% was obtained in the case of PEI-AuNPs, while PEI was cytotoxic. The PEI-AuNP is considered to be a potential candidate as a contrast agent for computed tomography.
URI
http://hdl.handle.net/20.500.11750/2142
Publisher
Polymer Society of Korea
Related Researcher
Files:
There are no files associated with this item.
Collection:
Magnetic-Controlled Materials Research Group1. Journal Articles
Division of IoT∙Robotics Convergence Research1. Journal Articles


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