Cited 16 time in
Cited 16 time in
Solid-state and solvent-free synthesis of azines, pyrazoles, and pyridazinones using solid hydrazine
- Solid-state and solvent-free synthesis of azines, pyrazoles, and pyridazinones using solid hydrazine
- Lee, B[Lee, Byeongno]; Kang, P[Kang, Philjun]; Lee, KH[Lee, Kyu Hyung]; Cho, J[Cho, Jaeheung]; Nam, W[Nam, Wonwoo]; Lee, WK[Lee, Won Koo]; Hur, NH[Hur, Nam Hwi]
- DGIST Authors
- Cho, J[Cho, Jaeheung]
- Issue Date
- Tetrahedron Letters, 54(11), 1384-1388
- Article Type
- 1,2 Dicarbonyl Derivative; Azine Derivative; Azines; Carbon Dioxide; Catalyst; Chemical Structure; Functional Group; Hydrazine; Pyrazole Derivative; Pyrazoles; Pyridazinone Derivative; Pyridazinones; Solid State; Solid State Reaction; Solvent; Solvent-Free Conditions; Synthesis; Unclassified Drug; Water
- Azines, pyrazoles, and pyridazinones were isolated as the sole products in high yields (>97%) by grinding solid hydrazine (H3N +NHCO2 -) with di-carbonyl compounds or by their reaction in the absence of solvent. Neither catalysts nor additives were needed to promote the reactions. The solid-state and solvent-free reactions proceeded under ambient conditions and did not produce any wastes other than water and carbon dioxide. They are operationally easy, environmentally safe, and readily scalable, allowing for highly selective synthesis of compounds containing the hydrazine motif. Copyright© 2012 Published by Elsevier Ltd.
- Elsevier Ltd
There are no files associated with this item.
- Emerging Materials ScienceETC1. Journal Articles
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.