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Near-field acoustic microbead trapping as remote anchor for single particle manipulation

Title
Near-field acoustic microbead trapping as remote anchor for single particle manipulation
Authors
Hwang, J.Y.[Hwang, Jae Youn]Cheon, D.Y.[Cheon, Dong Young]Shin, H.[Shin, Hyun June]Kim, H.B.[Kim, Hyun Bin]Lee, J.[Lee, Jung Woo]
DGIST Authors
Hwang, J.Y.[Hwang, Jae Youn]
Issue Date
2015
Citation
Applied Physics Letters, 106(18)
Type
Article
Article Type
Article
Keywords
Cellular ReactionsDiscrete FrequenciesDriving FrequenciesExperimental ValidationsFocused UltrasoundMaximum DisplacementMechanical DisturbanceMobile SecurityNear-Field AcousticsPolystyrenesTransducersUltrasonic Applications
ISSN
0003-6951
Abstract
We recently proposed an analytical model of a two-dimensional acoustic trapping of polystyrene beads in the ray acoustics regime, where a bead diameter is larger than the wavelength used. As its experimental validation, this paper demonstrates the transverse (or lateral) trapping of individual polystyrene beads in the near field of focused ultrasound. A 100 μm bead is immobilized on the central beam axis by a focused sound beam from a 30 MHz single element lithium niobate transducer, after being laterally displaced through hundreds of micrometers. Maximum displacement, a longest lateral distance at which a trapped bead can be directed towards the central axis, is thus measured over a discrete frequency range from 24 MHz to 36 MHz. The displacement data are found to be between 323.7 μm and 470.2 μm, depending on the transducer's driving frequency and input voltage amplitude. The experimental results are compared with their corresponding model values, and their relative errors lie between 0.9% and 3.9%. The results suggest that this remote maneuvering technique may be employed to manipulate individual cells through solid microbeads, provoking certain cellular reactions to localized mechanical disturbance without direct contact. © 2015 AIP Publishing LLC.
URI
http://hdl.handle.net/20.500.11750/2962
DOI
10.1063/1.4919802
Publisher
American Institute of Physics Inc.
Related Researcher
  • Author Hwang, Jae Youn MBIS(Multimodal Biomedical Imaging and System) Laboratory
  • Research Interests
Files:
There are no files associated with this item.
Collection:
Information and Communication EngineeringETC1. Journal Articles


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