Cited 6 time in
Cited 6 time in
Optimization of magnetic switches for single particle and cell transport
- Optimization of magnetic switches for single particle and cell transport
- Abedini-Nassab, R[Abedini-Nassab, Roozbeh]; Murdoch, DM[Murdoch, David M.]; Kim, C[Kim, CheolGi]; Yellen, BB[Yellen, Benjamin B.]
- DGIST Authors
- Kim, C[Kim, CheolGi]
- Issue Date
- Journal of Applied Physics, 115(24)
- Article Type
- Cells; Control Mechanism; Current Lines; Cytology; Device Geometries; Magnetic Devices; Magnetic Particle; Magnetic Switches; Nanomagnetics; Optimization Analysis; Particle Size Analysis; Single Particle; Stochastic Systems; Stochastic Variation
- The ability to manipulate an ensemble of single particles and cells is a key aim of lab-on-a-chip research; however, the control mechanisms must be optimized for minimal power consumption to enable future large-scale implementation. Recently, we demonstrated a matter transport platform, which uses overlaid patterns of magnetic films and metallic current lines to control magnetic particles and magnetic-nanoparticle-labeled cells; however, we have made no prior attempts to optimize the device geometry and power consumption. Here, we provide an optimization analysis of particle-switching devices based on stochastic variation in the particle's size and magnetic content. These results are immediately applicable to the design of robust, multiplexed platforms capable of transporting, sorting, and storing single cells in large arrays with low power and high efficiency. © 2014 AIP Publishing LLC.
- American Institute of Physics Publishing
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