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Magnetophoretic circuits for digital control of single particles and cells

Title
Magnetophoretic circuits for digital control of single particles and cells
Author(s)
Lim, ByeonghwaVenu, ReddyHu, XinghaoKim, KunwooJadhav, MitalAbedini-Nassab, RoozbehNoh, Young-WoockLim, Yong TaikYellen, Benjamin B.Kim, CheolGi
Issued Date
2014-05
Citation
Nature Communications, v.5
Type
Article
Keywords
SUPERPARAMAGNETIC BEADS DRIVENMANIPULATIONSEPARATIONPATHWAY
ISSN
2041-1723
Abstract
The ability to manipulate small fluid droplets, colloidal particles and single cells with the precision and parallelization of modern-day computer hardware has profound applications for biochemical detection, gene sequencing, chemical synthesis and highly parallel analysis of single cells. Drawing inspiration from general circuit theory and magnetic bubble technology, here we demonstrate a class of integrated circuits for executing sequential and parallel, timed operations on an ensemble of single particles and cells. The integrated circuits are constructed from lithographically defined, overlaid patterns of magnetic film and current lines. The magnetic patterns passively control particles similar to electrical conductors, diodes and capacitors. The current lines actively switch particles between different tracks similar to gated electrical transistors. When combined into arrays and driven by a rotating magnetic field clock, these integrated circuits have general multiplexing properties and enable the precise control of magnetizable objects. © 2014 Macmillan Publishers Limited.
URI
http://hdl.handle.net/20.500.11750/3093
DOI
10.1038/ncomms4846
Publisher
Nature Publishing Group
Related Researcher
  • 김철기 Kim, CheolGi
  • Research Interests Magnetic Materials and Spintronics; Converging Technology of Nanomaterials and Biomaterials; Bio-NEMS;MEMS
Files in This Item:
10.1038_ncomms4846.pdf

10.1038_ncomms4846.pdf

기타 데이터 / 1.79 MB / Adobe PDF download
Appears in Collections:
Department of Physics and Chemistry Lab for NanoBio-Materials & SpinTronics(nBEST) 1. Journal Articles

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