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Antimicrobial polyethyleneimine-silver nanoparticles in a stable colloidal dispersion

Title
Antimicrobial polyethyleneimine-silver nanoparticles in a stable colloidal dispersion
Authors
Lee, HJ[Lee, Hyun Ju]Lee, SG[Lee, Se Guen]Oh, EJ[Oh, Eun Jung]Chung, HY[Chung, Ho Yun]Han, SI[Han, Sang Ik]Kim, EJ[Kim, Eun Jung]Seo, SY[Seo, Song Yi]Do Ghim, H[Do Ghim, Han]Yeum, JH[Yeum, Jeong Hyun]Choi, JH[Choi, Jin Hyun]
DGIST Authors
Lee, HJ[Lee, Hyun Ju]; Lee, SG[Lee, Se Guen]
Issue Date
2011-11-01
Citation
Colloids and Surfaces B: Biointerfaces, 88(1), 505-511
Type
Article
Article Type
Article
ISSN
0927-7765
Abstract
Excellent colloidal stability and antimicrobial activity are important parameters for silver nanoparticles (AgNPs) in a range of biomedical applications. In this study, polyethyleneimine (PEI)-capped silver nanoparticles (PEI-AgNPs) were synthesized in the presence of sodium borohydride (NaBH 4) and PEI at room temperature. The PEI-AgNPs had a positive zeta potential of approximately +49mV, and formed a stable nanocolloid against agglomeration due to electrostatic repulsion. The particle size and hydrodynamic cluster size showed significant correlations with the amount of PEI and NaBH 4. PEI-AgNPs and even PEI showed excellent antimicrobial activity against Staphylococus aureus and Klebsiella pneumoniae. The cytotoxic effects of PEI and PEI-AgNPs were confirmed by an evaluation of the cell viability. The results suggest that the amount of PEI should be minimized to the level that maintains the stability of PEI-AgNPs in a colloidal dispersion. © 2011 Elsevier B.V.
URI
http://hdl.handle.net/20.500.11750/3429
DOI
10.1016/j.colsurfb.2011.07.041
Publisher
ELSEVIER SCIENCE BV
Related Researcher
Files:
There are no files associated with this item.
Collection:
Division of Nano∙Energy Convergence Research1. Journal Articles
Magnetic-Controlled Materials Research Group1. Journal Articles


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