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Natural magnetic nanoparticle containing droplet for smart drug delivery and heat treatment

Title
Natural magnetic nanoparticle containing droplet for smart drug delivery and heat treatment
Authors
Lee, Su WonAhn, Jae HyunChoi, Hong SooSeo, Jong MoCho, Dong IlKoo, K.
DGIST Authors
Choi, Hong Soo
Issue Date
2015
Citation
37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, 2015-November, 3541-3544
Type
Conference
Article Type
Conference Paper
ISBN
9780000000000
ISSN
1557-170X
Abstract
Biodegradable polymer droplet containing natural magnetic nanoparticle is composed for smart drug delivery and heat treatment. For selective and efficient drug delivery to the target tissue, direct high magnetic field will be applied near the target tissue. For drug release control and heat treatment, alternative high magnetic field will be applied. Magnetosome, natural magnetic nanoparticle, is extracted from magnetotactic bacteria, AMB-1. Mixture of magnetosome and sodium alginate composes into droplet using the microfluidic device applied Plateau-Rayleigh instability principle. The magnetosome contained droplet selected its rout at the bifurcate microchannels by direct high magnetic field. High alternative magnetic field generating circuit is designed with 18 mT and 4 Hz magnetic wave. The generated magnetic wave was applied to the extracted magnetosomes so that temperature of the magnetosomes increased from 15.2°C to 17.6°C. © 2015 IEEE.
URI
http://hdl.handle.net/20.500.11750/3703
DOI
10.1109/EMBC.2015.7319157
Publisher
Institute of Electrical and Electronics Engineers Inc.
Related Researcher
  • Author Choi, Hong Soo Bio-Micro Robotics Lab
  • Research Interests Micro/Nano robot; Neural prostheses; MEMS; BMI; MEMS/NEMS; BioMEMS; MEMS 초음파 트랜스듀스; 인공와우
Files:
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Collection:
Robotics EngineeringETC2. Conference Papers


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