Acoustic Radiation Force Impulse System based on Ultra-fast Acoustic Tweezers for Measurement of Cell Mechanics
- Title
- Acoustic Radiation Force Impulse System based on Ultra-fast Acoustic Tweezers for Measurement of Cell Mechanics
- Author(s)
- HeeYeon Park
- DGIST Authors
- HeeYeon Park ; Jae Youn Hwang ; Jin Ho Chang
- Advisor
- 황재윤
- Co-Advisor(s)
- Jin Ho Chang
- Issued Date
- 2023
- Awarded Date
- 2023-08-01
- Type
- Thesis
- Description
- Acoustic radiation force impulse system; Acoustic tweezer; Quantitative phase imaging; Cell mechanics; Poisson’s ratio; 음향 방사력 임펄스 시스템; 음향 핀셋; 정량적 위상 이미징; 세포 역학; 포아송 비
- Table Of Contents
-
Ⅰ. Introduction 1
Ⅱ. Methods 7
2.1 High-frequency Ultrasound Transducer 7
2.2 Suspended Cell Preparation 9
2.3 Acoustic Radiation Force Impulse System based on Acoustic Tweezers 10
2.4 Acoustic Tweezers Actuation and Cell Trapping Mechanisms 13
2.5 Image Processing using MATLAB 15
2.6 Calculation of The Strain and Poisson’s Ratio of a Trapped Cell 17
Ⅲ. Results 18
3.1 Cancer Cell Trapping by Acoustic Radiation, and Measurement of Cell Deformation Over Time Under Parameter Conditions 18
3.2 Comparison of Cell Length and Thickness Variations of MCF-7 and MDA-MB-231 21
3.3 Calculation and Analysis of Poisson's Ratio of MCF-7 and MDA-MB-231 23
3.4 Comparison of Thickness and Length Measurements of MCF-7 and MDA-MB-231 at Each Acoustic Pressure and Their Corresponding Deformation 25
3.5 Measurement of Poisson's Ratio of MCF-7 and MDA-MB-231 at Each Acoustic Pressure 28
Ⅳ. Conclusion 31
Ⅴ. Discussion 37
References 40
국문요약문 42
- URI
-
http://hdl.handle.net/20.500.11750/46442
http://dgist.dcollection.net/common/orgView/200000688298
- Degree
- Master
- Publisher
- DGIST
- Related Researcher
-
-
Hwang, Jae Youn
- Research Interests Multimodal Imaging; High-Frequency Ultrasound Microbeam; Ultrasound Imaging and Analysis; 스마트 헬스케어; Biomedical optical system
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- Files in This Item:
-
There are no files associated with this item.
- Appears in Collections:
- Department of Electrical Engineering and Computer Science Theses Master
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