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dc.contributor.author Lee, Ga Hyun ko
dc.contributor.author Lee, Sung June ko
dc.contributor.author Jeong, Sang Won ko
dc.contributor.author Kim, Hyun-Chul ko
dc.contributor.author Choi, Jin Hyun ko
dc.contributor.author Lee, Se Geun ko
dc.date.accessioned 2018-01-25T01:09:38Z -
dc.date.available 2018-01-25T01:09:38Z -
dc.date.created 2017-04-10 -
dc.date.issued 2015-11 -
dc.identifier.citation Polymer: Korea, v.39, no.6, pp.934 - 939 -
dc.identifier.issn 0379-153X -
dc.identifier.uri http://hdl.handle.net/20.500.11750/5158 -
dc.description.abstract Polylactic acid (PLA) films have been widely used in medical devices for surgical treatments. However, their use has been associated with complications, such as inflammation around the PLA film implant area. Several antioxidant agents have been incorporated on the surface of PLA films to suppress initial excessive inflammatory reactions through the quenching of reactive oxygen species (ROS) released from macrophages. The suppression of inflammation was evaluated by measuring the levels of various pro-inflammatory cytokines produced by the macrophages. In addition, by measuring quercetin release behavior, we determined the optimum type and molecular weight of the film coating polymer for the effective suppression of inflammation. These results suggest that the incorporation and controlled release of quercetin could be a promising method to reduce inflammation induced by PLA films. © 2015 The Polymer Society of Korea. All rights reserved. -
dc.publisher Polymer Society of Korea -
dc.subject Anti-Inflammatory -
dc.subject Antioxidant -
dc.subject Controlled Release -
dc.subject Implantation -
dc.subject PLA Film -
dc.title Inhibitory Effects of an Antioxidant Coating on a Polylactic Acid Film on Inflammatory Cytokines from Macrophage -
dc.title.alternative Inhibitory Effects of an Antioxidant Coating on a Polylactic Acid Film on Inflammatory Cytokines from Macrophage -
dc.type Article -
dc.identifier.doi 10.7317/pk.2015.39.6.934 -
dc.identifier.wosid 000366076200015 -
dc.identifier.scopusid 2-s2.0-84953304106 -
dc.type.local Article(Overseas) -
dc.type.rims ART -
dc.description.journalClass 1 -
dc.identifier.kciid ART002048378 -
dc.contributor.nonIdAuthor Lee, Ga Hyun -
dc.contributor.nonIdAuthor Choi, Jin Hyun -
dc.identifier.citationVolume 39 -
dc.identifier.citationNumber 6 -
dc.identifier.citationStartPage 934 -
dc.identifier.citationEndPage 939 -
dc.identifier.citationTitle Polymer: Korea -
dc.type.journalArticle Article -
dc.contributor.affiliatedAuthor Lee, Sung June -
dc.contributor.affiliatedAuthor Jeong, Sang Won -
dc.contributor.affiliatedAuthor Kim, Hyun-Chul -
dc.contributor.affiliatedAuthor Lee, Se Geun -
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Magnet-Controlled Materials Research Group 1. Journal Articles

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