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Optical methods for blood perfusion measurement-theoretical comparison among four different modalities
- Optical methods for blood perfusion measurement-theoretical comparison among four different modalities
- Bi, Renzhe; Dong, Jing; Poh, Chueh Loo; Lee, Kijoon
- DGIST Authors
- Lee, Kijoon
- Issue Date
- Journal of the Optical Society of America A: Optics and Image Science, and Vision, 32(5), 860-866
- Article Type
- Blood Circulation; Circulation; Comparative Study; Fluorescence Imaging; Human; Humans; Laser; Laser-Doppler Flowmetry; Laser Doppler Flowmetry; Lasers; Light Related Phenomena; Optical Imaging; Optical Processes; Procedures; Spectroscopy; Spectrum Analysis
- Blood perfusion in human tissue can be measured in vivo by means of various optical methods, which seem to be very different from one another. The most prominent examples of them are laser Doppler flowmetry, laser speckle contrast imaging, diffuse correlation spectroscopy, and the most recently developed diffuse speckle contrast analysis. In this paper, we claim that these four seemingly different modalities are examining different aspects of the same entity - the temporal autocorrelation function of scattered photons. We will show how the observables in each modality can be theoretically derived from the temporal autocorrelation function, and will discuss the merits and drawbacks of each modality in its practical use. © 2015 Optical Society of America.
- OSA - The Optical Society
- Related Researcher
Lee, Ki Joon
Biomedical Optics; DOT; DSCA; NIRS; OCT; LSCI; Nonlinear Optics; Random Laser; Coherent Backscattering
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