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dc.contributor.author Lee, Seung Min -
dc.contributor.author Kim, Soyeun -
dc.contributor.author Kim, Sang Won -
dc.contributor.author Kim, Jin Young -
dc.contributor.author Moon, Che Il -
dc.contributor.author Nelson, Bradley J. -
dc.contributor.author Choi, Hong Soo -
dc.date.available 2018-03-09T05:18:17Z -
dc.date.created 2018-03-05 -
dc.date.issued 2018-05 -
dc.identifier.citation Advanced Healthcare Materials, v.7, no.9 -
dc.identifier.issn 2192-2640 -
dc.identifier.uri http://hdl.handle.net/20.500.11750/5927 -
dc.description.abstract A capsule-type microrobot exhibits pick-and-drop (P&D) motion to hold a particle within a confined volume and transports it via a corkscrewing motion. The P&D motion is possible because the capsule-type microrobot has two parts: a plunger and a cap. The fabricated microrobots are wirelessly controlled by a magnetic manipulator. Drugs or cells can be encapsulated in the container of the capsule-type microrobot by the P&D motion or attached to the surface of the cap, which can be used as a supporting structure. Therefore, the capsule-type microrobot can deliver suspended or adherent cells. The drug or cells are minimally exposed or not completely exposed to the surrounding fluid and do not experience shear force when encapsulated in the container. As a proof-of-concept, secure transportation of microparticles in the confined volume of the capsule via P&D motion is demonstrated. In addition, the cap is used as a scaffold for neuronal cell culture on a rat brain slice to demonstrate its biocompatibility and feasibility for targeted cell delivery. The proposed capsule-type microrobot is suitable for diverse applications, as it protects the encapsulated materials. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. -
dc.language English -
dc.publisher John Wiley and Sons Ltd -
dc.title A Capsule-Type Microrobot with Pick-and-Drop Motion for Targeted Drug and Cell Delivery -
dc.type Article -
dc.identifier.doi 10.1002/adhm.201700985 -
dc.identifier.wosid 000431960000001 -
dc.identifier.scopusid 2-s2.0-85042169529 -
dc.type.local Article(Overseas) -
dc.type.rims ART -
dc.description.journalClass 1 -
dc.citation.publicationname Advanced Healthcare Materials -
dc.contributor.nonIdAuthor Lee, Seung Min -
dc.contributor.nonIdAuthor Kim, Soyeun -
dc.contributor.nonIdAuthor Kim, Sang Won -
dc.contributor.nonIdAuthor Nelson, Bradley J. -
dc.identifier.citationVolume 7 -
dc.identifier.citationNumber 9 -
dc.identifier.citationTitle Advanced Healthcare Materials -
dc.type.journalArticle Article -
dc.description.isOpenAccess N -
dc.subject.keywordAuthor cell differentiation -
dc.subject.keywordAuthor laser lithography -
dc.subject.keywordAuthor magnetic manipulation -
dc.subject.keywordAuthor microrobots -
dc.subject.keywordAuthor targeted cell transportation -
dc.subject.keywordPlus MAGNETIC MICROROBOTS -
dc.subject.keywordPlus MANIPULATION -
dc.subject.keywordPlus FABRICATION -
dc.subject.keywordPlus MICROMOTORS -
dc.subject.keywordPlus SWARM -
dc.contributor.affiliatedAuthor Lee, Seung Min -
dc.contributor.affiliatedAuthor Kim, Soyeun -
dc.contributor.affiliatedAuthor Kim, Sang Won -
dc.contributor.affiliatedAuthor Kim, Jin Young -
dc.contributor.affiliatedAuthor Moon, Che Il -
dc.contributor.affiliatedAuthor Nelson, Bradley J. -
dc.contributor.affiliatedAuthor Choi, Hong Soo -

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