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APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation

Article
APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation
  • Lee, Se-In ; 
  • Jeong, Woojin ; 
  • Lim, Heejin ; 
  • Cho, Sukhee ; 
  • Lee, Hyein ; 
  • Jang, Yonghee ; 
  • Cho, Joonho ; 
  • Bae, Simsung ; 
  • Lin, Yuan-Ta ; 
  • Tsai, Li-Huei ; 
    • et al
  • 2021-09
  • Lee, Se-In. (2021-09). APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation. Stem Cell Reports, 16(9), 2128–2137. doi: 10.1016/j.stemcr.2021.07.017
  • Cell Press
  • View : 832
  • Download : 65
Article
Enhanced differentiation of neural progenitor cells in Alzheimer's disease into vulnerable immature neurons
  • Cho, Joonho ; 
  • Bae, Simsung ; 
  • Jeon, Juyeong ; 
  • Transfeld, Janis ; 
  • Lee, Changyeob ; 
  • Nott, Alexi ; 
  • Gao, Fan ; 
  • Seo, Jinsoo
  • 2025-05
  • Cho, Joonho. (2025-05). Enhanced differentiation of neural progenitor cells in Alzheimer's disease into vulnerable immature neurons. iScience, 28(5). doi: 10.1016/j.isci.2025.112446
  • Cell Press
  • View : 121
  • Download : 0

Imaging lipid rafts reveals the principle of ApoE4-induced AR upregulation in human neurons

Article
Imaging lipid rafts reveals the principle of ApoE4-induced AR upregulation in human neurons
  • Lee, Se-In ; 
  • Lim, Heejin ; 
  • Kim, Na Yeon ; 
  • Yu, Jichang ; 
  • Cho, Joonho ; 
  • Lee, Hyein ; 
  • Moon, Dae Won ; 
  • Seo, Jinsoo
  • 2025-02
  • Lee, Se-In. (2025-02). Imaging lipid rafts reveals the principle of ApoE4-induced AR upregulation in human neurons. iScience, 28(2). doi: 10.1016/j.isci.2025.111893
  • Cell Press
  • View : 128
  • Download : 71
Article
Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation by modulating NLRP3, DYRK1A, and GSK3α/β
  • Park, Jin-Hee ; 
  • Hwang, Jeong-Woo ; 
  • Lee, Hyun-ju ; 
  • Jang, Geum Mi ; 
  • Jeong, Yoo Joo ; 
  • Cho, Joonho ; 
  • Seo, Jinsoo ; 
  • Hoe, Hyang-Sook
  • 2023-06
  • Park, Jin-Hee. (2023-06). Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation by modulating NLRP3, DYRK1A, and GSK3α/β. Frontiers in Immunology, 14. doi: 10.3389/fimmu.2023.1150940
  • Frontiers Media
  • View : 271
  • Download : 27
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