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Structurally engineered ultrasoft PEDOT:PSS fiber microelectrodes with enhanced electrochemical performance for neural interfaces
Stable and reliable neural interfacing is essential for the diagnosis and treatment of chronic neurological disorders. Flexible neural probes are particularly important for this purpose, as they minimize tissue damage and inflammatory responses while maintaining stable electrode-tissue coupling; however, achieving both high electrical performance and tissue-like mechanics remains challenging. Here, we present a poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) fiber microelectro
2026-05
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A robust vision language model for molecular status prediction and radiology report generation in adult-type diffuse gliomas
We aimed to establish a robust vision-language model ("Glio-LLaMA-Vision") for molecular status prediction and radiology report generation (RRG) in adult-type diffuse gliomas. Multiparametric MRI data and paired radiology reports from 1001 patients with adult-type diffuse gliomas were included in the institutional training set. A vision-language model, Glio-LLaMA-Vision, was developed from LLaMA 3.1 pre-trained on 2.79 million biomedical image-text pairs from PubMed Central and further fine-tune
2026-04
Shared and Divergent Transcriptional Programs of Oligodendrocyte Differentiation Across Vertebrate Species Revealed by scRNA-seq Analysis
A myelination is essential for neural function in the vertebrate central nervous system, yet the molecular details of how the oligodendrocyte differentiation program has evolved remain poorly understood. Here, we performed a cross-species single-cell transcriptomic analysis of oligodendrocyte lineage cells in the spinal cord of five vertebrate species: fugu, mudskipper, chicken, mouse, and human. Pseudotime trajectory analysis revealed a shared oligodendrocyte progenitor cell (OPC) to committed
2026-05
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AI-driven digital holographic microscopy for label-free quantitative cellular analysis: toward low-cost and field-deployable platforms
Recent progress in artificial intelligence (AI) and digital holographic microscopy (DHM) has enabled quantitative, label-free, and noninvasive cellular imaging with unprecedented precision. This review provides an overview of AI-driven DHM technologies that transform classical holographic phase reconstruction and cellular analysis into real-time, portable biomedical solutions. After outlining the optical and computational fundamentals of DHM and quantitative phase imaging, we describe how deep g
2026-05
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How to Use Library E-Resources Effectively
A manual guides you on searching, browsing, analyzing, and managing references using library resources and free search engines.
1) It deals with the differences, features, and usage of databases for searching journal articles such as Web of Science, SCOPUS, and Google Scholar.
2) It introduces JCR and Journal Impact Factor(JIF), which search for journal information and rankings.
3) It deals with managing references using reference tools such as EndNote and Mendeley.
4) A list
1) It deals with the differences, features, and usage of databases for searching journal articles such as Web of Science, SCOPUS, and Google Scholar.
2) It introduces JCR and Journal Impact Factor(JIF), which search for journal information and rankings.
3) It deals with managing references using reference tools such as EndNote and Mendeley.
4) A list
2022-07-12
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바이오 응용을 위한 초음파 및 광학 기반 다중 모달 영상 기술
이 연구는 초음파 광학 영상 기반의 다중 모달 영상 기술에 대한 최신 연구 동향과 응용 가능성에 대해 조사하였다. 초음파 영상은 실시간 영상 기능을 가지고 있으며 인체에 상대적으로 안전한 특성으로 인해 의료 분야에서 다양한질병의 진단에 사용되고 있다. 그러나 초음파 영상은 해상도가 낮은 한계가 있어 진단 정확도를 향상시키기 위해 다른광학 영상과의 결합을 통한 다중 모달 영상 기술 개발 연구가 진행되고 있다. 특히 초음파 광학 영상 기반의 다중 모달영상 기술은 각각의 영상 기법의 장점을 극대화하고 단점을 보완함으로써 질병 진단 정확도를 향상시킬 수 있는 수단으로 사용되고 있다. 이러한 기술은 초음파의 실시간 영상 기능과 광간섭 단층 영상 융합 기술, 초음파 광음향 다중 모달영상 기술, 초음파 형광 다중 모달 영상 기술, 초음파 형광 시정수 다중 모달 영상 기술 및 초음파 분광 다중 모달 영상기술 등 다양한 형태로 제안되고 있다. 본 연구에서는 이러한 초음파 광학 영상 기반의 다중 모달
2023-09
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Applications of flexible and stretchable three-dimensional structures for soft electronics
The development of devices that can be mechanically deformed in geometrical layouts, such as flexible/stretchable devices, is important for various applications. Conventional flexible/stretchable devices have been demonstrated using two-dimensional (2D) geometry, resulting in dimensional constraints on device operations and functionality limitations. Accordingly, expanding the dimensions in which such devices can operate and acquiring unique functionality that is difficult to implement in 2D pla
2023-06
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Signal Processing Design for Cochlear Implant System Using Piezoelectric Sensor
Today, the cochlear implant system is the most successful auditory prosthesis for the patients suffering hair cell loss or damage. The current cochlear implant system consists of an implantable electrode array for the stimulation and an external signal processor includ-ing a microphone and a battery. However, the conventional cochlear implant system is composed of a heavy signal processor. Furthermore, the exposure of an external signal processor causes a cosmetic problem to the patients. Theref
2014
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