Arabidopsis WSS1A, a DNA-protein crosslink repair protease, delays leaf senescence in cooperation with SUMO3
Park, Sanghoon
;
Oh, Hyunwoo
;
Jeong, Ukcheol
;
Lee, Jae Ho
;
Choi, Hyeyoung
;
Park, Hyunsu
;
Kim, Jinkwang
;
Kim, Yongmin
;
Kwak, Junmin
;
Yoon, Yeong Seon
;
Li, Zhonghai
;
Lee, Jong-Chan
;
Woo, Hye Ryun
Leaf senescence, the final stage of leaf development, is regulated by complex interplays of intrinsic genetic programs and environmental cues. Throughout their lifetimes, all living organisms encounter various endogenous and environmental challenges, many of which can cause potentially fatal DNA damage. Among these, DNA-protein crosslinks (DPCs) are particularly deleterious, as they obstruct essential processes such as replication and transcription, thereby compromising genome integrity and ulti