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Showing results 1 to 12 of 12

Article
Chronic oral administration of ibrutinib prevents long-term memory deficits and reduces AD pathology and neuroinflammatory responses in a mouse model of AD
  • Lee, Hyun-ju ; 
  • Kang, Sora ; 
  • Jeong, Yoo Joo ; 
  • Park, Jin-Hee ; 
  • Hwang, Jeong-Woo ; 
  • Gu, Chan-Hu ; 
  • Jung, Tae-Mi ; 
  • Oh, Seokjun ; 
  • Jang, Ji-Yeong ; 
  • Hoe, Hyang-Sook
  • 2025-07
  • Molecular Brain, v.18, no.1
  • BioMed Central
  • View : 996
  • Download : 0
Article
Current Status and Future Directions in the Development of Digital Therapeutic Interventions for Neurodevelopmental Disorders
  • Lee, Hyun-ju ; 
  • Jeong, Yoo Joo ; 
  • Kim, Jun-Su ; 
  • Kim, Seung-Jae ; 
  • Jo, Unhui ; 
  • Jun, Su Jin ; 
  • Lim, Jongmin ; 
  • Park, Jin-Yeop ; 
  • Lee, Myungji ; 
  • Kim, Donggi ; 
    • et al
  • 2025-06
  • Lee, Hyun-ju. (2025-06). Current Status and Future Directions in the Development of Digital Therapeutic Interventions for Neurodevelopmental Disorders. Clinical Pharmacology and Therapeutics, 117(6), 1632–1636. doi: 10.1002/cpt.3633
  • Wiley
  • View : 92
  • Download : 0

Dasatinib regulates LPS-induced microglial and astrocytic neuroinflammatory responses by inhibiting AKT/STAT3 signaling

Article
Dasatinib regulates LPS-induced microglial and astrocytic neuroinflammatory responses by inhibiting AKT/STAT3 signaling
  • Ryu, Ka-Young ; 
  • Lee, Hyun-Ju ; 
  • Woo, Hanwoong ; 
  • Kang, Ri-Jin ; 
  • Han, Kyung-Min ; 
  • Park, HyunHee ; 
  • Lee, Sang Min ; 
  • Lee, Ju-Young ; 
  • Jeong, Yoo Joo ; 
  • Nam, Hyun-Wook ; 
    • et al
  • 2019-10
  • Ryu, Ka-Young. (2019-10). Dasatinib regulates LPS-induced microglial and astrocytic neuroinflammatory responses by inhibiting AKT/STAT3 signaling. doi: 10.1186/s12974-019-1561-x
  • BioMed Central
  • View : 768
  • Download : 148

Developing theragnostics for Alzheimer's disease: Insights from cancer treatment

Article
Developing theragnostics for Alzheimer's disease: Insights from cancer treatment
  • Lee, Hyun-ju ; 
  • Choi, Hee-Jeong ; 
  • Jeong, Yoo Joo ; 
  • Na, Yoon-Hee ; 
  • Hong, Jin Tae ; 
  • Han, Ji Min ; 
  • Hoe, Hyang-Sook ; 
  • Lim, Key-Hwan
  • 2024-06
  • Lee, Hyun-ju. (2024-06). Developing theragnostics for Alzheimer's disease: Insights from cancer treatment. International Journal of Biological Macromolecules, 269. doi: 10.1016/j.ijbiomac.2024.131925
  • Elsevier
  • View : 182
  • Download : 81
Article
Digital Therapeutics for Alzheimer's and Parkinson's Diseases: Current Trends and Future Perspectives
  • Jeong, Yoo Joo ; 
  • Lee, Hyun-ju ; 
  • Kim, Jun-Su ; 
  • Kim, Seung-Jae ; 
  • Jo, Unhui ; 
  • Park, Jin Yeop ; 
  • Jun, Su Jin ; 
  • Lee, Won Seok ; 
  • Song, Mingoo ; 
  • Kim, Donggii ; 
    • et al
  • 2026-01
  • Medicinal Research Reviews, v.46, no.1, pp.316 - 327
  • Wiley
  • View : 100
  • Download : 0
Article
EGFR is a potential dual molecular target for cancer and Alzheimer’s disease
  • Choi, Hee-Jeong ; 
  • Jeong, Yoo Joo ; 
  • Kim, Jieun ; 
  • Hoe, Hyang-Sook
  • 2023-08
  • Choi, Hee-Jeong. (2023-08). EGFR is a potential dual molecular target for cancer and Alzheimer’s disease. Frontiers in Pharmacology, 14. doi: 10.3389/fphar.2023.1238639
  • Frontiers
  • View : 209
  • Download : 22

Erdafitinib diminishes LPS-mediated neuroinflammatory responses through NLRP3 in wild-type mice

Article
Erdafitinib diminishes LPS-mediated neuroinflammatory responses through NLRP3 in wild-type mice
  • Lee, Hyun-ju ; 
  • Kim, Se Ha ; 
  • Jung, Tae-Mi ; 
  • Kim, Yu-Jin ; 
  • Gu, Chan-Hu ; 
  • Jeong, Yoo Joo ; 
  • Song, Jeong-Heon ; 
  • Hoe, Hyang-Sook
  • 2025-06
  • Frontiers in Pharmacology, v.16
  • Frontiers Media
  • View : 1051
  • Download : 10

Erlotinib regulates short-term memory, tau/Aβ pathology, and astrogliosis in mouse models of AD

Article
Erlotinib regulates short-term memory, tau/Aβ pathology, and astrogliosis in mouse models of AD
  • Lee, Hyun-Ju ; 
  • Hwang, Jeong-Woo ; 
  • Kim, Jieun ; 
  • Jo, A-Ran ; 
  • Park, Jin-Hee ; 
  • Jeong, Yoo Joo ; 
  • Jang, Ji-Yeong ; 
  • Kim, Su-Jeong ; 
  • Song, Jeong-Heon ; 
  • Hoe, Hyang-Sook
  • 2024-10
  • Lee, Hyun-Ju. (2024-10). Erlotinib regulates short-term memory, tau/Aβ pathology, and astrogliosis in mouse models of AD. Frontiers in Immunology, 15. doi: 10.3389/fimmu.2024.1421455
  • Frontiers Media
  • View : 223
  • Download : 24

L-DOPA regulates neuroinflammation and Aβ pathology through NEP and ADAM17 in a mouse model of AD

Article
L-DOPA regulates neuroinflammation and Aβ pathology through NEP and ADAM17 in a mouse model of AD
  • Lee, Hyun-ju ; 
  • Nam, Jinhan ; 
  • Hwang, Jeong-Woo ; 
  • Park, Jin-Hee ; 
  • Jeong, Yoo Joo ; 
  • Jang, Ji-Yeong ; 
  • Kim, Su-Jeong ; 
  • Jo, A-Ran ; 
  • Hoe, Hyang-Sook
  • 2024-04
  • Lee, Hyun-ju. (2024-04). L-DOPA regulates neuroinflammation and Aβ pathology through NEP and ADAM17 in a mouse model of AD. Molecular Brain, 17(1). doi: 10.1186/s13041-024-01092-8
  • BioMed Central
  • View : 106
  • Download : 35
Article
Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation by modulating NLRP3, DYRK1A, and GSK3α/β
  • Park, Jin-Hee ; 
  • Hwang, Jeong-Woo ; 
  • Lee, Hyun-ju ; 
  • Jang, Geum Mi ; 
  • Jeong, Yoo Joo ; 
  • Cho, Joonho ; 
  • Seo, Jinsoo ; 
  • Hoe, Hyang-Sook
  • 2023-06
  • Park, Jin-Hee. (2023-06). Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation by modulating NLRP3, DYRK1A, and GSK3α/β. Frontiers in Immunology, 14. doi: 10.3389/fimmu.2023.1150940
  • Frontiers Media
  • View : 278
  • Download : 27
Article
Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD
  • Lee, Hyun-ju ; 
  • Hwang, Jeong-Woo ; 
  • Park, Jin-Hee ; 
  • Jeong, Yoo Joo ; 
  • Jang, Ji-Yeong ; 
  • Hoe, Hyang-Sook
  • 2023-08
  • Lee, Hyun-ju. (2023-08). Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD. Molecular Brain, 16(1). doi: 10.1186/s13041-023-01051-9
  • BioMed Central
  • View : 131
  • Download : 0

The dopamine analogue CA140 alleviates AD pathology, neuroinflammation, and rescues synaptic/cognitive functions by modulating DRD1 signaling or directly binding to Abeta

Article
The dopamine analogue CA140 alleviates AD pathology, neuroinflammation, and rescues synaptic/cognitive functions by modulating DRD1 signaling or directly binding to Abeta
  • Chae, Sehyun ; 
  • Lee, Hyun-ju ; 
  • Lee, Ha-Eun ; 
  • Kim, Jieun ; 
  • Jeong, Yoo Joo ; 
  • Lin, Yuxi ; 
  • Kim, Hye Yun ; 
  • Leriche, Geoffray ; 
  • Ehrlich, Rachel S. ; 
  • Lingl, Sascha Castro ; 
    • et al
  • 2024-08
  • Chae, Sehyun. (2024-08). The dopamine analogue CA140 alleviates AD pathology, neuroinflammation, and rescues synaptic/cognitive functions by modulating DRD1 signaling or directly binding to Abeta. Journal of Neuroinflammation, 21(1). doi: 10.1186/s12974-024-03180-x
  • BioMed Central
  • View : 255
  • Download : 43
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