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Showing results 1 to 12 of 12

Article

Chronic oral administration of ibrutinib prevents long-term memory deficits and reduces AD pathology and neuroinflammatory responses in a mouse model of AD

Lee, Hyun-ju ;
Kang, Sora ;
Jeong, Yoo Joo ;
Park, Jin-Hee ;
Hwang, Jeong-Woo ;
Gu, Chan-Hu ;
Jung, Tae-Mi ;
Oh, Seokjun ;
Jang, Ji-Yeong ;
Hoe, Hyang-Sook

2025-07
Molecular Brain, v.18, no.1
BioMed Central
View : 976
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Article

Current Status and Future Directions in the Development of Digital Therapeutic Interventions for Neurodevelopmental Disorders

Lee, Hyun-ju ;
Jeong, Yoo Joo ;
Kim, Jun-Su ;
Kim, Seung-Jae ;
Jo, Unhui ;
Jun, Su Jin ;
Lim, Jongmin ;
Park, Jin-Yeop ;
Lee, Myungji ;
Kim, Donggi ;

2025-06
Lee, Hyun-ju. (2025-06). Current Status and Future Directions in the Development of Digital Therapeutic Interventions for Neurodevelopmental Disorders. Clinical Pharmacology and Therapeutics, 117(6), 1632–1636. doi: 10.1002/cpt.3633
Wiley
View : 63
Download : 0

Article

Dasatinib regulates LPS-induced microglial and astrocytic neuroinflammatory responses by inhibiting AKT/STAT3 signaling

Ryu, Ka-Young ;
Lee, Hyun-Ju ;
Woo, Hanwoong ;
Kang, Ri-Jin ;
Han, Kyung-Min ;
Park, HyunHee ;
Lee, Sang Min ;
Lee, Ju-Young ;
Jeong, Yoo Joo ;
Nam, Hyun-Wook ;

2019-10
Ryu, Ka-Young. (2019-10). Dasatinib regulates LPS-induced microglial and astrocytic neuroinflammatory responses by inhibiting AKT/STAT3 signaling. doi: 10.1186/s12974-019-1561-x
BioMed Central
View : 753
Download : 128

Article

Developing theragnostics for Alzheimer's disease: Insights from cancer treatment

Lee, Hyun-ju ;
Choi, Hee-Jeong ;
Jeong, Yoo Joo ;
Na, Yoon-Hee ;
Hong, Jin Tae ;
Han, Ji Min ;
Hoe, Hyang-Sook ;
Lim, Key-Hwan

2024-06
Lee, Hyun-ju. (2024-06). Developing theragnostics for Alzheimer's disease: Insights from cancer treatment. International Journal of Biological Macromolecules, 269. doi: 10.1016/j.ijbiomac.2024.131925
Elsevier
View : 159
Download : 46

Article

Digital Therapeutics for Alzheimer's and Parkinson's Diseases: Current Trends and Future Perspectives

Jeong, Yoo Joo ;
Lee, Hyun-ju ;
Kim, Jun-Su ;
Kim, Seung-Jae ;
Jo, Unhui ;
Park, Jin Yeop ;
Jun, Su Jin ;
Lee, Won Seok ;
Song, Mingoo ;
Kim, Donggii ;

ACCEPT
Medicinal Research Reviews
Wiley
View : 71
Download : 0

Article

EGFR is a potential dual molecular target for cancer and Alzheimer’s disease

Choi, Hee-Jeong ;
Jeong, Yoo Joo ;
Kim, Jieun ;
Hoe, Hyang-Sook

2023-08
Choi, Hee-Jeong. (2023-08). EGFR is a potential dual molecular target for cancer and Alzheimer’s disease. Frontiers in Pharmacology, 14. doi: 10.3389/fphar.2023.1238639
Frontiers
View : 196
Download : 17

Article

Erdafitinib diminishes LPS-mediated neuroinflammatory responses through NLRP3 in wild-type mice

Lee, Hyun-ju ;
Kim, Se Ha ;
Jung, Tae-Mi ;
Kim, Yu-Jin ;
Gu, Chan-Hu ;
Jeong, Yoo Joo ;
Song, Jeong-Heon ;
Hoe, Hyang-Sook

2025-06
Lee, Hyun-ju. (2025-06). Erdafitinib diminishes LPS-mediated neuroinflammatory responses through NLRP3 in wild-type mice. Frontiers in Pharmacology, 16. doi: 10.3389/fphar.2025.1572604
Frontiers Media
View : 1020
Download : 0

Article

Erlotinib regulates short-term memory, tau/Aβ pathology, and astrogliosis in mouse models of AD

Lee, Hyun-Ju ;
Hwang, Jeong-Woo ;
Kim, Jieun ;
Jo, A-Ran ;
Park, Jin-Hee ;
Jeong, Yoo Joo ;
Jang, Ji-Yeong ;
Kim, Su-Jeong ;
Song, Jeong-Heon ;
Hoe, Hyang-Sook

2024-10
Lee, Hyun-Ju. (2024-10). Erlotinib regulates short-term memory, tau/Aβ pathology, and astrogliosis in mouse models of AD. Frontiers in Immunology, 15. doi: 10.3389/fimmu.2024.1421455
Frontiers Media
View : 195
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Article

L-DOPA regulates neuroinflammation and Aβ pathology through NEP and ADAM17 in a mouse model of AD

Lee, Hyun-ju ;
Nam, Jinhan ;
Hwang, Jeong-Woo ;
Park, Jin-Hee ;
Jeong, Yoo Joo ;
Jang, Ji-Yeong ;
Kim, Su-Jeong ;
Jo, A-Ran ;
Hoe, Hyang-Sook

2024-04
Lee, Hyun-ju. (2024-04). L-DOPA regulates neuroinflammation and Aβ pathology through NEP and ADAM17 in a mouse model of AD. Molecular Brain, 17(1). doi: 10.1186/s13041-024-01092-8
BioMed Central
View : 88
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Article

Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation by modulating NLRP3, DYRK1A, and GSK3α/β

Park, Jin-Hee ;
Hwang, Jeong-Woo ;
Lee, Hyun-ju ;
Jang, Geum Mi ;
Jeong, Yoo Joo ;
Cho, Joonho ;
Seo, Jinsoo ;
Hoe, Hyang-Sook

2023-06
Park, Jin-Hee. (2023-06). Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation by modulating NLRP3, DYRK1A, and GSK3α/β. Frontiers in Immunology, 14. doi: 10.3389/fimmu.2023.1150940
Frontiers Media
View : 255
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Article

Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD

Lee, Hyun-ju ;
Hwang, Jeong-Woo ;
Park, Jin-Hee ;
Jeong, Yoo Joo ;
Jang, Ji-Yeong ;
Hoe, Hyang-Sook

2023-08
Lee, Hyun-ju. (2023-08). Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD. Molecular Brain, 16(1). doi: 10.1186/s13041-023-01051-9
BioMed Central
View : 109
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Article

The dopamine analogue CA140 alleviates AD pathology, neuroinflammation, and rescues synaptic/cognitive functions by modulating DRD1 signaling or directly binding to Abeta

Chae, Sehyun ;
Lee, Hyun-ju ;
Lee, Ha-Eun ;
Kim, Jieun ;
Jeong, Yoo Joo ;
Lin, Yuxi ;
Kim, Hye Yun ;
Leriche, Geoffray ;
Ehrlich, Rachel S. ;
Lingl, Sascha Castro ;

2024-08
Chae, Sehyun. (2024-08). The dopamine analogue CA140 alleviates AD pathology, neuroinflammation, and rescues synaptic/cognitive functions by modulating DRD1 signaling or directly binding to Abeta. Journal of Neuroinflammation, 21(1). doi: 10.1186/s12974-024-03180-x
BioMed Central
View : 226
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