Browsing by Titles

Showing results 1 to 22 of 22

  • Lee, Hyun-ju ; 
  • Kang, Sora ; 
  • Jeong, Yoo Joo ; 
  • Jung, Tae-Mi ; 
  • Hwang, Jeong-Woo ; 
  • Jang, Ji-Yeong ; 
  • Gu, Chan-Hu ; 
  • Oh, Seokjun ; 
  • Song, Jeong-Heon ; 
  • Moon, Minho ; 
  • et al
  • 2026-03
  • FRONTIERS IN IMMUNOLOGY, v.17
  • FRONTIERS MEDIA SA
  • View : 75
  • Download : 0
  • Lee, Hyun-ju ; 
  • Kang, Sora ; 
  • Jeong, Yoo Joo ; 
  • Park, Jin-Hee ; 
  • Hwang, Jeong-Woo ; 
  • Gu, Chan-Hu ; 
  • Jung, Tae-Mi ; 
  • Oh, Seokjun ; 
  • Jang, Ji-Yeong ; 
  • Hoe, Hyang-Sook
  • 2025-07
  • Molecular Brain, v.18, no.1
  • BioMed Central
  • View : 1065
  • Download : 0
  • Lee, Hyun-ju ; 
  • Jeong, Yoo Joo ; 
  • Kim, Jun-Su ; 
  • Kim, Seung-Jae ; 
  • Jo, Unhui ; 
  • Jun, Su Jin ; 
  • Lim, Jongmin ; 
  • Park, Jin-Yeop ; 
  • Lee, Myungji ; 
  • Kim, Donggi ; 
  • et al
  • 2025-06
  • Lee, Hyun-ju. (2025-06). Current Status and Future Directions in the Development of Digital Therapeutic Interventions for Neurodevelopmental Disorders. Clinical Pharmacology and Therapeutics, 117(6), 1632–1636. doi: 10.1002/cpt.3633
  • Wiley
  • View : 175
  • Download : 0

Developing theragnostics for Alzheimer's disease: Insights from cancer treatment

  • Lee, Hyun-ju ; 
  • Choi, Hee-Jeong ; 
  • Jeong, Yoo Joo ; 
  • Na, Yoon-Hee ; 
  • Hong, Jin Tae ; 
  • Han, Ji Min ; 
  • Hoe, Hyang-Sook ; 
  • Lim, Key-Hwan
  • 2024-06
  • Lee, Hyun-ju. (2024-06). Developing theragnostics for Alzheimer's disease: Insights from cancer treatment. International Journal of Biological Macromolecules, 269. doi: 10.1016/j.ijbiomac.2024.131925
  • Elsevier
  • View : 281
  • Download : 236
  • Jeong, Yoo Joo ; 
  • Lee, Hyun-ju ; 
  • Kim, Jun-Su ; 
  • Kim, Seung-Jae ; 
  • Jo, Unhui ; 
  • Park, Jin Yeop ; 
  • Jun, Su Jin ; 
  • Lee, Won Seok ; 
  • Song, Mingoo ; 
  • Kim, Donggii ; 
  • et al
  • 2026-01
  • Medicinal Research Reviews, v.46, no.1, pp.316 - 327
  • Wiley
  • View : 199
  • Download : 0

Donepezil Regulates LPS and Aβ-Stimulated Neuroinflammation through MAPK/NLRP3 Inflammasome/STAT3 Signaling

  • Kim, Jieun ; 
  • Lee, Hyun-ju ; 
  • Park, Seon Kyeong ; 
  • Park, Jin-Hee ; 
  • Jeong, Ha-Ram ; 
  • Lee, Soojung ; 
  • Lee, Heeyong ; 
  • Seol, Eunyoung ; 
  • Hoe, Hyang-Sook
  • 2021-10
  • Kim, Jieun. (2021-10). Donepezil Regulates LPS and Aβ-Stimulated Neuroinflammation through MAPK/NLRP3 Inflammasome/STAT3 Signaling. doi: 10.3390/ijms221910637
  • Multidisciplinary Digital Publishing Institute (MDPI)
  • View : 549
  • Download : 172

Erdafitinib diminishes LPS-mediated neuroinflammatory responses through NLRP3 in wild-type mice

  • Lee, Hyun-ju ; 
  • Kim, Se Ha ; 
  • Jung, Tae-Mi ; 
  • Kim, Yu-Jin ; 
  • Gu, Chan-Hu ; 
  • Jeong, Yoo Joo ; 
  • Song, Jeong-Heon ; 
  • Hoe, Hyang-Sook
  • 2025-06
  • Frontiers in Pharmacology, v.16
  • Frontiers Media
  • View : 1162
  • Download : 69
  • Lee, Hyun-ju ; 
  • Jeon, Seong Gak ; 
  • Kim, Jieun ; 
  • Kang, Ri Jin ; 
  • Kim, Seong-Min ; 
  • Han, Kyung-Min ; 
  • Park, HyunHee ; 
  • Kim, Ki-taek ; 
  • Sung, You Me ; 
  • Nam, Hye Yeon ; 
  • et al
  • 2021-03
  • Lee, Hyun-ju. (2021-03). Ibrutinib modulates Aβ/tau pathology, neuroinflammation, and cognitive function in mouse models of Alzheimer's disease. Aging Cell, 20(3), e13332. doi: 10.1111/acel.13332
  • Blackwell Publishing Inc.
  • View : 584
  • Download : 0

Idebenone Decreases Aβ Pathology by Modulating RAGE/Caspase-3 Signaling and the Aβ Degradation Enzyme NEP in a Mouse Model of AD

  • Lee, Hyun-ju ; 
  • Jeong, Ha-Ram ; 
  • Park, Jin-Hee ; 
  • Hoe, Hyang-Sook
  • 2021-09
  • Lee, Hyun-ju. (2021-09). Idebenone Decreases Aβ Pathology by Modulating RAGE/Caspase-3 Signaling and the Aβ Degradation Enzyme NEP in a Mouse Model of AD. Biology, 10(9). doi: 10.3390/biology10090938
  • MDPI
  • View : 577
  • Download : 117
  • Lee, Hyun-ju ; 
  • Park, Jin-Hee ; 
  • Hoe, Hyang-Sook
  • 2022-02
  • Lee, Hyun-ju. (2022-02). Idebenone Regulates A beta and LPS-Induced Neurogliosis and Cognitive Function Through Inhibition of NLRP3 Inflammasome/IL-1 beta Axis Activation. Frontiers in Immunology, 13. doi: 10.3389/fimmu.2022.749336
  • Frontiers Media S.A.
  • View : 418
  • Download : 0
  • Lee, Hyun-ju ; 
  • Choi, Tae-Ik ; 
  • Kim, Yong-Min ; 
  • Lee, Soonje ; 
  • Han, Bing ; 
  • Bak, In Seon ; 
  • Moon, Sun Ae ; 
  • Yu, Dae-Yeul ; 
  • Shin, Ki Soon ; 
  • Kwon, Yunhee Kim ; 
  • et al
  • 2021-08
  • Lee, Hyun-ju. (2021-08). Identification of Gng8-expressing cell types in the MHb and IPN. Molecular Psychiatry, 26(8), 3665–3665. doi: 10.1038/s41380-021-01278-9
  • Nature Publishing Group
  • View : 680
  • Download : 0

Inhibition of CDK4/6 regulates AD pathology, neuroinflammation and cognitive function through DYRK1A/STAT3 signaling

  • Lee, Hyun-ju ; 
  • Hoe, Hyang-Sook
  • 2023-04
  • Lee, Hyun-ju. (2023-04). Inhibition of CDK4/6 regulates AD pathology, neuroinflammation and cognitive function through DYRK1A/STAT3 signaling. Pharmacological Research, 190. doi: 10.1016/j.phrs.2023.106725
  • Academic Press
  • View : 291
  • Download : 221

L-DOPA regulates neuroinflammation and Aβ pathology through NEP and ADAM17 in a mouse model of AD

  • Lee, Hyun-ju ; 
  • Nam, Jinhan ; 
  • Hwang, Jeong-Woo ; 
  • Park, Jin-Hee ; 
  • Jeong, Yoo Joo ; 
  • Jang, Ji-Yeong ; 
  • Kim, Su-Jeong ; 
  • Jo, A-Ran ; 
  • Hoe, Hyang-Sook
  • 2024-04
  • Lee, Hyun-ju. (2024-04). L-DOPA regulates neuroinflammation and Aβ pathology through NEP and ADAM17 in a mouse model of AD. Molecular Brain, 17(1). doi: 10.1186/s13041-024-01092-8
  • BioMed Central
  • View : 193
  • Download : 83
  • Park, Jin-Hee ; 
  • Hwang, Jeong-Woo ; 
  • Lee, Hyun-ju ; 
  • Jang, Geum Mi ; 
  • Jeong, Yoo Joo ; 
  • Cho, Joonho ; 
  • Seo, Jinsoo ; 
  • Hoe, Hyang-Sook
  • 2023-06
  • Park, Jin-Hee. (2023-06). Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation by modulating NLRP3, DYRK1A, and GSK3α/β. Frontiers in Immunology, 14. doi: 10.3389/fimmu.2023.1150940
  • Frontiers Media
  • View : 400
  • Download : 67
  • Kim, Jieun ; 
  • Lee, Hyun-ju ; 
  • Park, Jin-Hee ; 
  • Cha, Byung-Yoon ; 
  • Hoe, Hyang-Sook
  • 2022-07
  • Kim, Jieun. (2022-07). Nilotinib modulates LPS-induced cognitive impairment and neuroinflammatory responses by regulating P38/STAT3 signaling. Journal of Neuroinflammation, 19(1). doi: 10.1186/s12974-022-02549-0
  • BioMed Central
  • View : 440
  • Download : 0
  • Lee, Hyun-ju ; 
  • Hwang, Jeong-Woo ; 
  • Park, Jin-Hee ; 
  • Jeong, Yoo Joo ; 
  • Jang, Ji-Yeong ; 
  • Hoe, Hyang-Sook
  • 2023-08
  • Lee, Hyun-ju. (2023-08). Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD. Molecular Brain, 16(1). doi: 10.1186/s13041-023-01051-9
  • BioMed Central
  • View : 201
  • Download : 0
  • Lee, Hyun-ju ; 
  • Park, Jin-Hee ; 
  • Trotter, Justin H. ; 
  • Maher, James N. ; 
  • Keenoy, Kathleen E. ; 
  • Jang, You Mi ; 
  • Lee, Youngeun ; 
  • Kim, Jae-Ick ; 
  • Weeber, Edwin J. ; 
  • Hoe, Hyang-Sook
  • 2023-02
  • Lee, Hyun-ju. (2023-02). Reelin and APP Cooperatively Modulate Dendritic Spine Formation In Vitro and In Vivo. Experimental Neurobiology, 32(1), 42–55. doi: 10.5607/en22044
  • 한국뇌신경과학회
  • View : 412
  • Download : 0

Regorafenib Regulates AD Pathology, Neuroinflammation, and Dendritic Spinogenesis in Cells and a Mouse Model of AD

  • Han, Kyung-Min ; 
  • Kang, Ri Jin ; 
  • Jeon, Hyongjun ; 
  • Lee, Hyun-ju ; 
  • Lee, Ji-Soo ; 
  • Park, HyunHee ; 
  • Jeon, Seong Gak ; 
  • Suk, Kyoungho ; 
  • Seo, Jinsoo ; 
  • Hoe, Hyang-Sook
  • 2020-07
  • Han, Kyung-Min. (2020-07). Regorafenib Regulates AD Pathology, Neuroinflammation, and Dendritic Spinogenesis in Cells and a Mouse Model of AD. doi: 10.3390/cells9071655
  • MDPI AG
  • View : 805
  • Download : 263
  • Lee, Hyun-ju ; 
  • Choi, Tae-Ik ; 
  • Kim, Yong-Min ; 
  • Lee, Soonje ; 
  • Han, Bing ; 
  • Bak, In Seon ; 
  • Moon, Sun Ae ; 
  • Yu, Dae-Yeul ; 
  • Shin, Ki Soon ; 
  • Kim Kwon, Yunhee ; 
  • et al
  • 2021-08
  • Lee, Hyun-ju. (2021-08). Regulation of habenular G-protein gamma 8 on learning and memory via modulation of the central acetylcholine system. Molecular Psychiatry, 26(8), 3737–3750. doi: 10.1038/s41380-020-00893-2
  • Nature Publishing Group
  • View : 852
  • Download : 0

Repurposing ibrutinib: therapeutic effects and implications for translational approaches in Alzheimer's disease

  • Lee, Hyun-ju ; 
  • Hoe, Hyang-Sook
  • 2023-10
  • Lee, Hyun-ju. (2023-10). Repurposing ibrutinib: therapeutic effects and implications for translational approaches in Alzheimer's disease. Neural Regeneration Research, 18(10), 2194–2195. doi: 10.4103/1673-5374.369108
  • Neural Regeneration Research
  • View : 150
  • Download : 62

The dopamine analogue CA140 alleviates AD pathology, neuroinflammation, and rescues synaptic/cognitive functions by modulating DRD1 signaling or directly binding to Abeta

  • Chae, Sehyun ; 
  • Lee, Hyun-ju ; 
  • Lee, Ha-Eun ; 
  • Kim, Jieun ; 
  • Jeong, Yoo Joo ; 
  • Lin, Yuxi ; 
  • Kim, Hye Yun ; 
  • Leriche, Geoffray ; 
  • Ehrlich, Rachel S. ; 
  • Lingl, Sascha Castro ; 
  • et al
  • 2024-08
  • Chae, Sehyun. (2024-08). The dopamine analogue CA140 alleviates AD pathology, neuroinflammation, and rescues synaptic/cognitive functions by modulating DRD1 signaling or directly binding to Abeta. Journal of Neuroinflammation, 21(1). doi: 10.1186/s12974-024-03180-x
  • BioMed Central
  • View : 362
  • Download : 122
  • Lee, Hyun-ju ; 
  • Woo, Hanwoong ; 
  • Lee, Ha-Eun ; 
  • Jeon, Hyongjun ; 
  • Ryu, Ka-Young ; 
  • Nam, Jin han ; 
  • Jeon, Seong Gak ; 
  • Park, HyunHee ; 
  • Lee, Ji-Soo ; 
  • Han, Kyung-Min ; 
  • et al
  • 2020-11
  • Lee, Hyun-ju. (2020-11). The novel DYRK1A inhibitor KVN93 regulates cognitive function, amyloid-beta pathology, and neuroinflammation. doi: 10.1016/j.freeradbiomed.2020.08.030
  • Elsevier Inc.
  • View : 664
  • Download : 0
1