Title

Autonomous separation of bio-functionalized carriers by non-linear characteristics of micro-magnetic on-chip devices

Alternative Title

온 칩 디바이스의 비선형 자기 특성을 통한 바이오 기능화 된 이송자의 자율적인 분리

DGIST Authors

Kim, CheolGi ; Kim, Hyeonseol ; Kim, Dong-Ho

Advisor

김철기

Co-Advisor(s)

Dong-Ho Kim

Issued Date

2019

Awarded Date

2019-02

Citation

Hyeonseol Kim. (2019). Autonomous separation of bio-functionalized carriers by non-linear characteristics of micro-magnetic on-chip devices. doi: 10.22677/thesis.200000171462

Type

Thesis

Table Of Contents

Ⅰ . Introduction
1.1 Necessity of Single Cell Analysis(SCA)
1.2 Several techniques for SCA
1.3 Magnetophoretic technology using magnetic pattern

ⅠI. Simulation & Calculation
2.1 Effective magnetic field distance for Superparamagnetic particles
2.2 Finite difference method simulation
2.2.1 Center of Magnetism
2.3 Functionalized pattern design based on finite difference method
2.4 Expected results on Disaggregation

ⅠII. Experiment
3.1 Material & Experiment equipment
3.1.1 Material
3.1.2 Magnetic pattern fabrication
3.2 Experimental Setup
3.3 Magnetic beads(M-450) separation by Positive Magnetophoresis
3.4 Magnetic beads(M-280) separation by Positive Magnetophoresis
3.5 Non-magnetic beads separation by Negative Magnetophoresis
3.6 Separating only certain beads from beads of various sizes
3.7 Phase diagram of DSD wave pattern operation

ⅠV. Conclusion

URI

http://dgist.dcollection.net/common/orgView/200000171462
http://hdl.handle.net/20.500.11750/10706

DOI

10.22677/thesis.200000171462

Degree

MASTER

Department

Emerging Materials Science

Publisher

DGIST

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