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Autonomous separation of bio-functionalized carriers by non-linear characteristics of micro-magnetic on-chip devices

Title
Autonomous separation of bio-functionalized carriers by non-linear characteristics of micro-magnetic on-chip devices
Alternative Title
온 칩 디바이스의 비선형 자기 특성을 통한 바이오 기능화 된 이송자의 자율적인 분리
Author(s)
Hyeonseol Kim
DGIST Authors
Kim, CheolGiKim, HyeonseolKim, Dong-Ho
Advisor
김철기
Co-Advisor(s)
Dong-Ho Kim
Issued Date
2019
Awarded Date
2019-02
Type
Thesis
Table Of Contents
Ⅰ . Introduction
1.1 Necessity of Single Cell Analysis(SCA)
1.2 Several techniques for SCA
1.3 Magnetophoretic technology using magnetic pattern

ⅠI. Simulation & Calculation
2.1 Effective magnetic field distance for Superparamagnetic particles
2.2 Finite difference method simulation
2.2.1 Center of Magnetism
2.3 Functionalized pattern design based on finite difference method
2.4 Expected results on Disaggregation

ⅠII. Experiment
3.1 Material & Experiment equipment
3.1.1 Material
3.1.2 Magnetic pattern fabrication
3.2 Experimental Setup
3.3 Magnetic beads(M-450) separation by Positive Magnetophoresis
3.4 Magnetic beads(M-280) separation by Positive Magnetophoresis
3.5 Non-magnetic beads separation by Negative Magnetophoresis
3.6 Separating only certain beads from beads of various sizes
3.7 Phase diagram of DSD wave pattern operation

ⅠV. Conclusion
URI
http://dgist.dcollection.net/common/orgView/200000171462

http://hdl.handle.net/20.500.11750/10706
DOI
10.22677/thesis.200000171462
Degree
MASTER
Department
Emerging Materials Science
Publisher
DGIST
Related Researcher
  • 김철기 Kim, CheolGi
  • Research Interests Magnetic Materials and Spintronics; Converging Technology of Nanomaterials and Biomaterials; Bio-NEMS;MEMS
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Department of Physics and Chemistry Theses Master

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