Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Park, Jihyo | - |
dc.contributor.author | Moon, Haeram | - |
dc.contributor.author | Hong, Seonki | - |
dc.date.accessioned | 2019-12-16T01:11:50Z | - |
dc.date.available | 2019-12-16T01:11:50Z | - |
dc.date.created | 2019-12-06 | - |
dc.date.issued | 2019-12 | - |
dc.identifier.issn | 1226-4601 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11750/10996 | - |
dc.description.abstract | Background: Melanins are a group of biopigments in microorganisms that generate a wide range of colorants. Due to their multifunctionality, including ultraviolet protection, radical scavenging, and photothermal conversion, in addition to their intrinsic biocompatibility, natural melanins and synthetic melanin-like nanomaterials have been suggested as novel nano-bio platforms in biomedical applications. Main body: Recent approaches in the synthesis of melanin-like nanomaterials and their biomedical applications have briefly been reviewed. Melanin-like nanomaterials have been suggested as endogenous chromophores for photoacoustic imaging and radical scavengers for the treatment of inflammatory diseases. The photothermal conversion ability of these materials under near-infrared irradiation allows hyperthermia-mediated cancer treatments, and their intrinsic fluorescence can be an indicator in biosensing applications. Furthermore, catechol-rich melanin and melanin-like nanomaterials possess a versatile affinity for various functional organic and inorganic additives, allowing the design of multifunctional hybrid nanomaterials that expand their range of applications in bioimaging, therapy, theranostics, and biosensing. Conclusion: Melanin-like natural and synthetic nanomaterials have emerged; however, the under-elucidated chemical structures of these materials are still a major obstacle to the construction of novel nanomaterials through bottom-up approaches and tuning the material properties at the molecular level. Further advancements in melanin-based medical applications can be achieved with the incorporation of next-generation chemical and molecular analytical tools. © 2019 The Author(s). | - |
dc.language | English | - |
dc.publisher | The Korean Society for Biomaterials | BioMed Central | - |
dc.title | Recent advances in melanin-like nanomaterials in biomedical applications: a mini review | - |
dc.type | Article | - |
dc.identifier.doi | 10.1186/s40824-019-0175-9 | - |
dc.identifier.scopusid | 2-s2.0-85076036887 | - |
dc.identifier.bibliographicCitation | Biomaterials Research, v.23, no.1 | - |
dc.identifier.kciid | ART002542893 | - |
dc.description.isOpenAccess | TRUE | - |
dc.subject.keywordAuthor | Melanin | - |
dc.subject.keywordAuthor | Polydopamine | - |
dc.subject.keywordAuthor | Bioimaging | - |
dc.subject.keywordAuthor | Theranostics | - |
dc.subject.keywordAuthor | Drug delivery | - |
dc.subject.keywordAuthor | Biosensing | - |
dc.citation.number | 1 | - |
dc.citation.title | Biomaterials Research | - |
dc.citation.volume | 23 | - |
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