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상온과 상압에서 퍼옥소 코발트 복합체를 사용하여 나이트릴 관능기를 하이드록사믹 엑시드 관능기로 전환시키는 방법

Title
상온과 상압에서 퍼옥소 코발트 복합체를 사용하여 나이트릴 관능기를 하이드록사믹 엑시드 관능기로 전환시키는 방법
Translated Title
A method of converting a nitrile functional group into a hydroxamic functional group by using a peroxocobalt complex at room temperature and normal pressure
Inventors
노현주조재흥
DGIST Inventors
조재흥
Country
US
Application Date
2018-10-10
Application No.
16-156967
Registration Date
2019-09-03
Registration No.
10-399-928
Assignee
(재)대구경북과학기술원(100/100)
URI
http://hdl.handle.net/20.500.11750/11156
Abstract
The method of the present invention for converting a nitrile functional group into a hydroxamic acid functional group can be easily performed at room temperature and under normal pressure by using a peroxocobalt complex. The final hydroxamic acid functional group produced through the intermediate Hydroximatocobalt (III) compound or the derivative comprising the same has been known to be able to inhibit the growth of cancer cells, so that the conversion method of the present invention can be applied to the preparation of a pro-drug for anticancer treatment.
Files:
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Collection:
Department of Emerging Materials ScienceBiomimetic Materials Laboratory3. Patents


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