Cited 4 time in webofscience Cited 3 time in scopus

Regulation of stomatal development by stomatal lineage miRNAs

Title
Regulation of stomatal development by stomatal lineage miRNAs
Authors
Zhu, JialiPark, Ji-HwanLee, SeulbeeLee, Jae HoHwang, DaeheeKwak, June MyoungKim, Yun Ju
DGIST Authors
Hwang, Daehee; Kwak, June Myoung
Issue Date
2020-03
Citation
Proceedings of the National Academy of Sciences of the United States of America, 117(11), 6237-6245
Type
Article
Article Type
Article
Author Keywords
PHO2stomatal developmentstomatal lineage miRNA
Keywords
PHOSPHATE HOMEOSTASISCELL-DIFFERENTIATIONMEDIATED REGULATIONSECRETORY PEPTIDESMALL RNASPLANTMICRORNADIVISIONTERMINATIONCOMPONENTS
ISSN
0027-8424
Abstract
Stomata in the plant epidermis play a critical role in growth and survival by controlling gas exchange, transpiration, and immunity to pathogens. Plants modulate stomatal cell fate and patterning through key transcriptional factors and signaling pathways. MicroRNAs (miRNAs) are known to contribute to developmental plasticity in multicellular organisms; however, no miRNAs appear to target the known regulators of stomatal development. It remains unclear as to whether miRNAs are involved in stomatal development. Here, we report highly dynamic, developmentally stage-specific miRNA expression profiles from stomatal lineage cells. We demonstrate that stomatal lineage miRNAs positively and negatively regulate stomatal formation and patterning to avoid clustered stomata. Target prediction of stomatal lineage miRNAs implicates potential cellular processes in stomatal development. We show that miR399-mediated PHO2 regulation, involved in phosphate homeostasis, contributes to the control of stomatal development. Our study demonstrates that miRNAs constitute a critical component in the regulatory mechanisms controlling stomatal development. © 2020 National Academy of Sciences. All rights reserved.
URI
http://hdl.handle.net/20.500.11750/11653
DOI
10.1073/pnas.1919722117
Publisher
National Academy of Sciences
Related Researcher
  • Author Kwak, June Myoung Lab of Cell Signaling and Development
  • Research Interests Calcium Signaling; ABA;ROS Signaling; plant development; Development of Abscission; Culluar Features; Signaling network; Environmental Regulation
Files:
Collection:
Department of New BiologySystems Biology and Medicine Lab1. Journal Articles
Department of New BiologyLab of Cell Signaling and Development1. Journal Articles


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