Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Baek, Seung Hee | - |
dc.contributor.author | Song, Hyun Woo | - |
dc.contributor.author | Lee, Sunwoong | - |
dc.contributor.author | Kim, Jung-Eun | - |
dc.contributor.author | Kim, Yeo Hyang | - |
dc.contributor.author | Wi, Jung-Sub | - |
dc.contributor.author | Ok, Jong G. | - |
dc.contributor.author | Park, Jun Seok | - |
dc.contributor.author | Hong, Seonki | - |
dc.contributor.author | Kwak, Moon Kyu | - |
dc.contributor.author | Lee, Hye Jin | - |
dc.contributor.author | Nam, Sung-Wook | - |
dc.date.accessioned | 2020-07-20T01:52:10Z | - |
dc.date.available | 2020-07-20T01:52:10Z | - |
dc.date.created | 2020-06-30 | - |
dc.date.issued | 2020-05 | - |
dc.identifier.citation | Frontiers in Chemistry, v.8, pp.285 | - |
dc.identifier.issn | 2296-2646 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11750/12102 | - |
dc.description.abstract | Localized surface plasmon resonance (LSPR) is a powerful platform for detecting biomolecules including proteins, nucleotides, and vesicles. Here, we report a colloidal gold (Au) nanoparticle-based assay that enhances the LSPR signal of nanoimprinted Au strips. The binding of the colloidal Au nanoparticle on the Au strip causes a red-shift of the LSPR extinction peak, enabling the detection of interleukin-10 (IL-10) cytokine. For LSPR sensor fabrication, we employed a roll-to-roll nanoimprinting process to create nanograting structures on polyethylene terephthalate (PET) film. By the angled deposition of Au on the PET film, we demonstrated a double-bent Au structure with a strong LSPR extinction peak at ~760 nm. Using the Au LSPR sensor, we developed an enzyme-linked immunosorbent assay (ELISA) protocol by forming a sandwich structure of IL-10 capture antibody/IL-10/IL-10 detection antibody. To enhance the LSPR signal, we introduced colloidal Au nanocube (AuNC) to be cross-linked with IL-10 detection antibody for immunogold assay. Using IL-10 as a model protein, we successfully achieved nanomolar sensitivity. We confirmed that the shift of the extinction peak was improved by 450% due to plasmon coupling between AuNC and Au strip. We expect that the AuNC-assisted LSPR sensor platform can be utilized as a diagnostic tool by providing convenient and fast detection of the LSPR signal. © Copyright © 2020 Baek, Song, Lee, Kim, Kim, Wi, Ok, Park, Hong, Kwak, Lee and Nam. | - |
dc.language | English | - |
dc.publisher | Frontiers Media S.A. | - |
dc.title | Gold Nanoparticle-Enhanced and Roll-to-Roll Nanoimprinted LSPR Platform for Detecting Interleukin-10 | - |
dc.type | Article | - |
dc.identifier.doi | 10.3389/fchem.2020.00285 | - |
dc.identifier.wosid | 000540613600001 | - |
dc.identifier.scopusid | 2-s2.0-85086223543 | - |
dc.type.local | Article(Overseas) | - |
dc.type.rims | ART | - |
dc.description.journalClass | 1 | - |
dc.citation.publicationname | Frontiers in Chemistry | - |
dc.contributor.nonIdAuthor | Baek, Seung Hee | - |
dc.contributor.nonIdAuthor | Song, Hyun Woo | - |
dc.contributor.nonIdAuthor | Lee, Sunwoong | - |
dc.contributor.nonIdAuthor | Kim, Jung-Eun | - |
dc.contributor.nonIdAuthor | Kim, Yeo Hyang | - |
dc.contributor.nonIdAuthor | Wi, Jung-Sub | - |
dc.contributor.nonIdAuthor | Ok, Jong G. | - |
dc.contributor.nonIdAuthor | Park, Jun Seok | - |
dc.contributor.nonIdAuthor | Kwak, Moon Kyu | - |
dc.contributor.nonIdAuthor | Lee, Hye Jin | - |
dc.contributor.nonIdAuthor | Nam, Sung-Wook | - |
dc.identifier.citationVolume | 8 | - |
dc.identifier.citationStartPage | 285 | - |
dc.identifier.citationTitle | Frontiers in Chemistry | - |
dc.type.journalArticle | Article | - |
dc.description.isOpenAccess | Y | - |
dc.subject.keywordAuthor | Au nanocube | - |
dc.subject.keywordAuthor | IL-10 | - |
dc.subject.keywordAuthor | Au LSPR strip | - |
dc.subject.keywordAuthor | roll-to-roll | - |
dc.subject.keywordAuthor | nanoarchitecture | - |
dc.subject.keywordPlus | SURFACE-PLASMON RESONANCE | - |
dc.subject.keywordPlus | RANGE | - |
dc.contributor.affiliatedAuthor | Baek, Seung Hee | - |
dc.contributor.affiliatedAuthor | Song, Hyun Woo | - |
dc.contributor.affiliatedAuthor | Lee, Sunwoong | - |
dc.contributor.affiliatedAuthor | Kim, Jung-Eun | - |
dc.contributor.affiliatedAuthor | Kim, Yeo Hyang | - |
dc.contributor.affiliatedAuthor | Wi, Jung-Sub | - |
dc.contributor.affiliatedAuthor | Ok, Jong G. | - |
dc.contributor.affiliatedAuthor | Park, Jun Seok | - |
dc.contributor.affiliatedAuthor | Hong, Seonki | - |
dc.contributor.affiliatedAuthor | Kwak, Moon Kyu | - |
dc.contributor.affiliatedAuthor | Lee, Hye Jin | - |
dc.contributor.affiliatedAuthor | Nam, Sung-Wook | - |