The purpose of this study were to examine the influence of social suport and stress of university students participating in physical education classes on self-regulation and communication. To achieve the purpose of this research, the research subjects selected 319 university students participating in physical education classes in Seoul, Gyeonggi, Chungcheong, and Daegu using quota sampling method. Based on previous studies, a hypothetical model of the study was constructed. Social support and stress were included as exogenous variables. Self-regulation and communication were included as endogenous variables. Measurement variables for theoretical variables were 14, and confirmatory analysis and reliability analysis were conducted as measurement tools. To analyze data, I conducted analysis using SPSS 21.0 for Windows and LISREL(liner structural relationship; ver. 8.80). The results obtained through this process were as follows. First, self-regulation and communication increase as the social support of university students participating in physical education classes increases. Second, self-regulation and communication increase as the stress of university students participating in physical education classes decreases. Finally, communication increases as the self-regulation of university students participating in physical education classes increases.