Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Abbas, Mohamed Ali Ahmed | - |
dc.contributor.author | Ramulu, Torati Sri | - |
dc.contributor.author | Lee, Chang Soo | - |
dc.contributor.author | Rinaldi, Carlos | - |
dc.contributor.author | Kim, CheolGi | - |
dc.date.accessioned | 2021-04-26T05:01:32Z | - |
dc.date.available | 2021-04-26T05:01:32Z | - |
dc.date.created | 2018-03-29 | - |
dc.date.issued | 2014-11 | - |
dc.identifier.issn | 2157-7439 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11750/13375 | - |
dc.description.abstract | Magnetic nanoparticles are frequently coated with SiO2 to improve their stability, biocompatibility and functionality for they become promising for many biomedical applications, such as MR imaging contrast agents, magnetically-targeted drug delivery vehicles, agents for hyperthermia, etc. In our study, we demonstrated a novel and time reducing modified sol-gel approach for obtaining a uniform Fe3O4/SiO2 core/shell nanocubes. Furthermore, the thickness of the silica shell is easily controlled in the range of 5-16 nm by adjusting the reaction parameters. The core/shell nanocubes samples were characterized by X-ray diffractometry (XRD), Transmission Electron Microscopy (TEM), Energy Dispersive Spectrometer (EDS), fourier transform infrared spectroscopy (FTIR), and vibrating sample magnetometer (VSM). The as-prepared Fe3O4/SiO2 core/shell nanocubes showed good stability in air for at least 4 month as well as against annealing condition of up to 300°C in presence of H2 gas as a strong reducing agent. Furthermore, high magnetization value of 50.7 emu/g was obtained for the sample with thin silica thickness (5 nm) as a consequence of shell thickness controlled. Moreover, the biocompatibility of the core/shell nanocube was enhanced in comparison to that of pristine Fe3O4 nanocubes. In addition, the Fe3O4/SiO2 nanocubes were functionalized by Aminopropy-ltriethoxysilane, and then conjugated with streptavidin-Cy3 successfully as indicated by fluorescence microscopy. |
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dc.language | English | - |
dc.publisher | OMICS Publishing Group | - |
dc.title | Fe3O4/SiO2 Core/Shell Nanocubes: Novel Coating Approach with Tunable Silica Thickness and Enhancement in Stability and Biocompatibility | - |
dc.type | Article | - |
dc.identifier.doi | 10.4172/2157-7439.1000244 | - |
dc.identifier.bibliographicCitation | Journal of Nanomedicine & Nanotechnology, v.5, no.6, pp.244 - 244 | - |
dc.description.isOpenAccess | TRUE | - |
dc.subject.keywordAuthor | Magnetic properties | - |
dc.subject.keywordAuthor | Fe3 O4 /SiO2 nanocubes | - |
dc.subject.keywordAuthor | Core/shell | - |
dc.subject.keywordAuthor | Bio-compatibility | - |
dc.subject.keywordAuthor | Stability | - |
dc.citation.endPage | 244 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 244 | - |
dc.citation.title | Journal of Nanomedicine & Nanotechnology | - |
dc.citation.volume | 5 | - |
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