Cited time in webofscience Cited time in scopus

Magnetophoretic Micro-Distributor for Controlled Clustering of Cells

Title
Magnetophoretic Micro-Distributor for Controlled Clustering of Cells
Author(s)
Yoon, JonghwanKang, YuminKim, HyeonseolTorati, Sri RamuluKim, KeonmokLim, ByeonghwaKim, CheolGi
Issued Date
2022-02
Citation
Advanced Science, v.9, no.6
Type
Article
Author Keywords
cell clusteringcell-cell interactionlab-on-a-chipmagnetophoresissingle-cell manipulation
Keywords
ON-CHIPDURATIONSYSTEM
ISSN
2198-3844
Abstract
Cell clustering techniques are important to produce artificial cell clusters for in vitro models of intercellular mechanisms at the single-cell level. The analyses considering physical variables such as the shape and size of cells have been very limited. In addition, the precise manipulation of cells and control of the physical variables are still challenging. In this paper, a magnetophoretic device consisting of a trampoline micromagnet and active elements that enable the control of individual selective jumping motion and positioning of a micro-object is proposed. Based on a numerical simulation under various conditions, automatic separation or selective clustering of micro-objects according to their sizes is performed by parallel control and programmable manipulation. This method provides efficient control of the physical variables of cells and grouping of cells with the desired size and number, which can be a milestone for a better understanding of the intercellular dynamics between clustered cells at the single-cell level for future cell-on-chip applications.
URI
http://hdl.handle.net/20.500.11750/15952
DOI
10.1002/advs.202103579
Publisher
Wiley-VCH Verlag
Related Researcher
  • 김철기 Kim, CheolGi
  • Research Interests Magnetic Materials and Spintronics; Converging Technology of Nanomaterials and Biomaterials; Bio-NEMS;MEMS
Files in This Item:

There are no files associated with this item.

Appears in Collections:
Department of Physics and Chemistry Lab for NanoBio-Materials & SpinTronics(nBEST) 1. Journal Articles

qrcode

  • twitter
  • facebook
  • mendeley

Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE