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Ambient Mass Spectrometry Imaging of Small Molecules from Cells and Tissues
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dc.contributor.author Kim, Jae Young -
dc.contributor.author Lim, Heejin -
dc.contributor.author Moon, DaeWon -
dc.date.accessioned 2022-01-14T08:30:01Z -
dc.date.available 2022-01-14T08:30:01Z -
dc.date.created 2022-01-07 -
dc.date.issued 2022-01 -
dc.identifier.issn 1064-3745 -
dc.identifier.uri http://hdl.handle.net/20.500.11750/16094 -
dc.description.abstract New methods to analyze cells and tissues in ambient condition without any harsh chemical fixation or physical freezing and drying are summarized in this report. The first approach, an atmospheric pressure mass spectrometry imaging method, is based on laser ablation in atmospheric pressure assisted by atmospheric plasma and nanomaterials such as nanoparticles and graphene to enhance laser ablation. The second one is based on secondary ion mass spectrometry (SIMS) imaging of live cells in solution capped with single-layer graphene to preserve intact and hydrated biological samples even under ultrahigh vacuum for SIMS bio-imaging in solution. © 2022, The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature. -
dc.language English -
dc.publisher Humana Press, Inc. -
dc.title Ambient Mass Spectrometry Imaging of Small Molecules from Cells and Tissues -
dc.type Article -
dc.identifier.doi 10.1007/978-1-0716-2030-4_3 -
dc.identifier.scopusid 2-s2.0-85121529263 -
dc.identifier.bibliographicCitation Kim, Jae Young. (2022-01). Ambient Mass Spectrometry Imaging of Small Molecules from Cells and Tissues. Methods in Molecular Biology, 2437, 41–59. doi: 10.1007/978-1-0716-2030-4_3 -
dc.description.isOpenAccess FALSE -
dc.subject.keywordAuthor Laser ablation -
dc.subject.keywordAuthor Nanomaterials -
dc.subject.keywordAuthor Secondary ion mass spectrometry -
dc.subject.keywordAuthor Single-layer graphene -
dc.subject.keywordAuthor Ambient mass spectrometric imaging -
dc.subject.keywordAuthor Atmospheric pressure mass spectrometry imaging -
dc.citation.endPage 59 -
dc.citation.startPage 41 -
dc.citation.title Methods in Molecular Biology -
dc.citation.volume 2437 -
dc.description.journalRegisteredClass scopus -
dc.relation.journalResearchArea Chemistry -
dc.relation.journalWebOfScienceCategory Chemistry, Physical -
dc.type.docType Book Chapter -
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