Title

Gelation-based Naked-eye Detection of Glucose via Enzymatic Quinone Tanning of Catechol-conjugated Biopolymers

Alternative Title

카테콜 결합 생체 고분자의 효소적 퀴논 태닝을 통한 포도당의 겔화 기반 육안 검출

DGIST Authors

Jisoo Lee ; Seonki Hong ; Jinhee Park

Advisor

홍선기

Co-Advisor(s)

Jinhee Park

Issued Date

2022

Awarded Date

2022/02

Citation

Jisoo Lee. (2022). Gelation-based Naked-eye Detection of Glucose via Enzymatic Quinone Tanning of Catechol-conjugated Biopolymers. doi: 10.22677/thesis.200000592054

Type

Thesis

Subject

diabetes, glucose, glucose oxidase, quinone tanning, catechol-conjugated polymer, naked-eye detection, single step

Description

diabetes, glucose, glucose oxidase, quinone tanning, catechol-conjugated polymer, naked-eye detection, single step

Table Of Contents

Ⅰ. Introduction 1
Ⅱ. Experimental Section 4
2.1 Materials 4
2.2 Synthesis of catechol-conjugated polyethylene glycol 4
2.3 HRP/H2O2-mediated gelation system 5
2.4 GOx-coupled gelation system 5
2.5 Characterization 6
2.5.1 Porosity measurement 6
2.5.2 Swelling behavior 6
2.5.3 Rheological analysis 7
2.6 Gelation-based glucose detection in human serum 7
2.7 Selectivity and stability test 8
III. Results and Discussion 9
3.1 Synthesis of catechol-conjugated polyethylene glycol 9
3.2 HRP-mediated gelation of catechol-conjugated polyethylene glycol 10
3.3 Glucose-triggered enzymatic gelation 12
3.4 Characterization of hydrogel 15
3.5 Gelation-based one-pot, single-step glucose assay 19
IV. Conclusion 23
Reference 24
요약문 25

URI

http://dgist.dcollection.net/common/orgView/200000592054
http://hdl.handle.net/20.500.11750/16285

DOI

10.22677/thesis.200000592054

Degree

Master

Department

Emerging Materials Science

Publisher

DGIST

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