WEB OF SCIENCE
SCOPUS
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | 김종경 | - |
| dc.contributor.author | Somi Kim | - |
| dc.date.accessioned | 2022-03-07T16:00:30Z | - |
| dc.date.available | 2022-03-07T16:00:30Z | - |
| dc.date.issued | 2022 | - |
| dc.identifier.uri | http://dgist.dcollection.net/common/orgView/200000591934 | en_US |
| dc.identifier.uri | http://hdl.handle.net/20.500.11750/16308 | - |
| dc.description | stomach,gastric chief cells,base stem cells,stem cell quiescence,p57,scRNA-seq | - |
| dc.description.statementofresponsibility | N | - |
| dc.description.tableofcontents | I. Introduction 1 1.1 The structure of stomach epithelium 1 1.2 The stem cell population in stomach epithelium 1 1.3 Damage response of base stem cells in stomach epithelium 1 II. Preliminary data 2 2.1. Essential gene alterations happen in Troy+ chief cells during injury repair 2 2.2. p57-expressing chief cells directly undergo transition to injury-responsive chief cells upon injury 2 2.3. p57 induces reserve stem cell-like state in gastric corpus organoids 3 III. Methods 3 3.1. Animals 3 3.2. Animal treatments 4 3.3. Library preparation and bulk RNA-seq in Troy+ chief cells 4 3.4. Generation of single-cell RNA-seq data 4 3.5. Time-course RNA-seq data analysis 4 3.6. scRNA-seq data preprocessing 6 3.7. scRNA-seq data analysis 7 IV. Results 8 4.1. Rapid transcriptional changes happen in Troy+ chief cells during injury repair 8 4.2. Single-cell transcriptomic analysis defines a specific injury-responsive chief cell population 11 V. Discussion 16 References 18 |
- |
| dc.format.extent | 23 | - |
| dc.language | eng | - |
| dc.publisher | DGIST | - |
| dc.subject | stomach,gastric chief cells,base stem cells,stem cell quiescence,p57,scRNA-seq | - |
| dc.title | p57 is a molecular switch of adult stem cell quiescence in mouse stomach | - |
| dc.type | Thesis | - |
| dc.identifier.doi | 10.22677/thesis.200000591934 | - |
| dc.description.degree | Master | - |
| dc.contributor.department | New Biology | - |
| dc.identifier.bibliographicCitation | Somi Kim. (2022). p57 is a molecular switch of adult stem cell quiescence in mouse stomach. doi: 10.22677/thesis.200000591934 | - |
| dc.contributor.coadvisor | JaeHyung Koo | - |
| dc.date.awarded | 2022/02 | - |
| dc.publisher.location | Daegu | - |
| dc.description.database | dCollection | - |
| dc.citation | XT.NM 김55 202202 | - |
| dc.date.accepted | 1/21/22 | - |
| dc.contributor.alternativeDepartment | 뉴바이올로지전공 | - |
| dc.embargo.liftdate | 20260228 | - |
| dc.contributor.affiliatedAuthor | Somi Kim | - |
| dc.contributor.affiliatedAuthor | Jong Kyoung Kim | - |
| dc.contributor.affiliatedAuthor | JaeHyung Koo | - |
| dc.contributor.alternativeName | 김소미 | - |
| dc.contributor.alternativeName | Jong Kyoung Kim | - |
| dc.contributor.alternativeName | 구재형 | - |
