Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | 김종경 | - |
| dc.contributor.author | Dong Gon Cha | - |
| dc.date.accessioned | 2022-03-07T16:00:40Z | - |
| dc.date.available | 2022-03-07T16:00:40Z | - |
| dc.date.issued | 2022 | - |
| dc.identifier.uri | http://dgist.dcollection.net/common/orgView/200000591876 | en_US |
| dc.identifier.uri | http://hdl.handle.net/20.500.11750/16326 | - |
| dc.description | scRNA-seq, Barrier to autointegration factor (Baf), chromatin organization, neural progenitor competence, neurodevelopment | - |
| dc.description.statementofresponsibility | N | - |
| dc.description.tableofcontents | I. Introduction 1 II. Preliminaries 3 2.1 Drosophila neuroblasts with Baf knockdown shows abnormal chromatin organization and formation of neuroblast clones 3 2.2 pan-neuronal knockdown of Baf induces marked reduction of excitatory neurons at the adult stage 3 2.3 Neuronal knockdown of Baf induces behavioral abnormalities at the adult stage 4 III. Results 5 3.1 scRNA-seq identifies cell types in neuronal lineage from control and Baf KD Drosophila 5 3.2 Baf knockdown induces transcriptional changes in Type I neuroblasts 7 3.3 Type I neuroblast-specific neurodevelopment is impaired by Baf knockdown 8 IV. Discussion 11 V. Materials and methods 13 5.1 Sample preparation for single-cell sequencing 13 5.2 scRNA-seq data preprocessing 13 5.3 scRNA-seq data analysis 14 References 15 요약문 20 |
- |
| dc.format.extent | 20 | - |
| dc.language | eng | - |
| dc.publisher | DGIST | - |
| dc.subject | scRNA-seq, Barrier to autointegration factor (Baf), chromatin organization, neural progenitor competence, neurodevelopment | - |
| dc.title | Single-cell RNA sequencing reveals that Baf contributes to neural progenitor competence of Drosophila nervous system in a lineage-specific manner | - |
| dc.title.alternative | 단일 세포 전사체 분석을 통한 Drosophila 신경계 내에서 Baf가 계통특이적 신경전구세포 분화능에 미치는 영향에 관한 연구 | - |
| dc.type | Thesis | - |
| dc.identifier.doi | 10.22677/thesis.200000591876 | - |
| dc.description.degree | Master | - |
| dc.contributor.department | New Biology | - |
| dc.contributor.coadvisor | June M. Kwak | - |
| dc.date.awarded | 2022/02 | - |
| dc.publisher.location | Daegu | - |
| dc.description.database | dCollection | - |
| dc.citation | XT.NM 차25 202202 | - |
| dc.date.accepted | 1/21/22 | - |
| dc.contributor.alternativeDepartment | 뉴바이올로지전공 | - |
| dc.embargo.liftdate | 20240228 | - |
| dc.contributor.affiliatedAuthor | Dong Gon Cha | - |
| dc.contributor.affiliatedAuthor | Jong Kyoung Kim | - |
| dc.contributor.affiliatedAuthor | June M. Kwak | - |
| dc.contributor.alternativeName | 차동곤 | - |
| dc.contributor.alternativeName | Jong Kyoung Kim | - |
| dc.contributor.alternativeName | 곽준명 | - |
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