Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Ok, Mirae | - |
dc.contributor.author | Kim, Ka Young | - |
dc.contributor.author | Choi, Heekyoung | - |
dc.contributor.author | Kim, Seonghan | - |
dc.contributor.author | Lee, Shim Sung | - |
dc.contributor.author | Cho, Jaeheung | - |
dc.contributor.author | Jung, Sung Ho | - |
dc.contributor.author | Jung, Jong Hwa | - |
dc.date.accessioned | 2022-07-06T02:33:36Z | - |
dc.date.available | 2022-07-06T02:33:36Z | - |
dc.date.created | 2022-03-03 | - |
dc.date.issued | 2022-03 | - |
dc.identifier.issn | 2041-6520 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11750/16510 | - |
dc.description.abstract | The study of chiral self-sorting is extremely important for understanding biological systems and for developing applications for the biomedical field. In this study, we attempted unprecedented chiral self-sorting supramolecular polymerization accompanying helical inversion with Ag+ in one enantiomeric component. Bola-type terpyridine-based ligands (R-L-1 and S-L-1) comprising R- or S-alanine analogs were synthesized. First, R-L-1 dissolved in DMSO/H2O (1 : 1, v/v) forms right-handed helical fibers (aggregate I) via supramolecular polymerization. However, after the addition of AgNO3 (0.2-1.1 equiv.) to the R-L-1 ligand, in particular, it was found that aggregate II with left-handed helicity is generated from the [R-L-1(AgNO3)(2)] complex through the [R-(LAg)-Ag-1](+) complex via the dissociation of aggregate I by a multistep with an off pathway, thus demonstrating interesting self-sorting properties driven by helicity and shape discrimination. In addition, the [R-L-1(AgNO3)(2)] complex, which acted as a building block to generate aggregate III with a spherical structure, existed as a metastable product during the formation of aggregate II in the presence of 1.2-1.5 equiv. of AgNO3. Furthermore, the AFM and CD results of two samples prepared using aggregates I and III with different volume ratios were similar to those obtained upon the addition of AgNO3 to free R-L-1. These findings suggest that homochiral self-sorting in a mixture system occurred by the generation of aggregate II composed of the [R-(LAg)-Ag-1](+) complex via the rearrangement of both, aggregates I and III. This is a unique example of helicity- and shape-driven chiral self-sorting supramolecular polymerization induced by Ag+ starting from one enantiomeric component. This research will improve understanding of homochirality in complex biological models and contribute to the development of new chiral materials and catalysts for asymmetric synthesis. | - |
dc.language | English | - |
dc.publisher | Royal Society of Chemistry | - |
dc.title | Helicity-driven chiral self-sorting supramolecular polymerization with Ag+: right- and left-helical aggregates | - |
dc.type | Article | - |
dc.identifier.doi | 10.1039/d1sc06413d | - |
dc.identifier.wosid | 000755934400001 | - |
dc.identifier.scopusid | 2-s2.0-85127343946 | - |
dc.identifier.bibliographicCitation | Chemical Science, v.13, no.11, pp.3109 - 3117 | - |
dc.description.isOpenAccess | TRUE | - |
dc.subject.keywordPlus | FRAMEWORKS | - |
dc.subject.keywordPlus | MODEL | - |
dc.subject.keywordPlus | DRUG | - |
dc.subject.keywordPlus | PATHWAY COMPLEXITY | - |
dc.subject.keywordPlus | SILVER(I) | - |
dc.subject.keywordPlus | POLYMERS | - |
dc.subject.keywordPlus | TRANSFORMATION | - |
dc.citation.endPage | 3117 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 3109 | - |
dc.citation.title | Chemical Science | - |
dc.citation.volume | 13 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.type.docType | Article | - |