Title

Hydroxamate Transfer and Oxidative Reactivity of Cobalt and Iron Complexes in Biomimetic Model Chemistry

Alternative Title

생체 모방화학을 활용한 코발트와 철 착물의 하이드록사메이트 전달과 산화반응성

DGIST Authors

Nam Kwon ; Nak Cheon Jeong ; Jaeheung Cho

Advisor

정낙천

Co-Advisor(s)

Jaeheung Cho

Issued Date

2021

Awarded Date

2021/02

Citation

Nam Kwon. (2021). Hydroxamate Transfer and Oxidative Reactivity of Cobalt and Iron Complexes in Biomimetic Model Chemistry. doi: 10.22677/thesis.200000361891

Type

Thesis

Subject

Metalloenzyme, Biomimetic chemistry, Cobalt prodrug, Drug delivery mechanism, Reactive diiron-dioxygen complex, Amphoteric reactivity, 금속 효소, 생체 모방 화학, 코발트 프로드러그, 약물 전달반응, 이핵 철 이산소 화합물, 양쪽성 반응

Table Of Contents

General Introduction 1
Chapter 1. Mechanistic Insight into Hydroxamate Transfer Reaction Mimicking the Inhibition of Zinc-Containing Enzymes 16
1.1. Abstract. 16
1.2. Introduction 18
1.3. Results and Discussion. 20
1.4. Conclusion. 48
1.5. Experimental Section 49
1.6. References 58
Chapter 2. Amphoteric Reactivity in Nucleophilic and Electrophilic Oxidation of Diiron Peroxo Complex 63
2.1. Abstract 63
2.2. Introduction 64
2.3. Results and Discussion. 66
2.4. Conclusion 71
2.5. Experimental Section 72
2.6. References 74
Concluding Remarks 78
Acknowledgement 80

URI

http://dgist.dcollection.net/common/orgView/200000361891
http://hdl.handle.net/20.500.11750/16648

DOI

10.22677/thesis.200000361891

Degree

Doctor

Department

Emerging Materials Science

Publisher

DGIST

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