Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Jin, Siwoo | - |
dc.contributor.author | Park, Jiseong | - |
dc.contributor.author | Lee, Wonhee John | - |
dc.contributor.author | Ahn, Yongdeok | - |
dc.contributor.author | Park, Youngchan | - |
dc.contributor.author | Park, Minsoo | - |
dc.contributor.author | Hwang, Inchan | - |
dc.contributor.author | Seo, Kwanyong | - |
dc.contributor.author | Seo, Daeha | - |
dc.date.accessioned | 2022-08-25T02:00:00Z | - |
dc.date.available | 2022-08-25T02:00:00Z | - |
dc.date.created | 2022-06-29 | - |
dc.date.issued | 2022-05 | - |
dc.identifier.issn | 2691-3704 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11750/16819 | - |
dc.description.abstract | Live video recording of intracellular material transport is a promising means of deciphering the fascinating underlying mechanisms driving life at the molecular level. Such technology holds the key to realizing real-time observation at appropriate resolutions in three-dimensional (3D) space within living cells. Here, we report an optical microscopic method for probing endosomal dynamics with proper spatiotemporal resolution within 3D space in live cells: plasmonic dark -field STORM (pdf-STORM). We first confirmed that pdf-STORM has a spatial resolution comparable to that of scanning electron microscopy. Additionally, by observing two optical probes within a single organelle, we were able to track rotational movements and demonstrate the feasibility of using pdf-STORM to observe the angular displacements of an endosome during a "tug-of-war" over an extended period. Finally, we show various biophysical parameters of the hitherto unelucidated dynamics of endosomes-angular displacement is discontinuous and y-axis movement predominates and follows a long-tail distribution. © 2022 American Chemical Society. All rights reserved. | - |
dc.language | English | - |
dc.publisher | American Chemical Society | - |
dc.title | Two GPSes in a Ball: Deciphering the Endosomal Tug-of-War Using Plasmonic Dark-Field STORM | - |
dc.type | Article | - |
dc.identifier.doi | 10.1021/jacsau.2c00180 | - |
dc.identifier.wosid | 000819385100001 | - |
dc.identifier.scopusid | 2-s2.0-85143798829 | - |
dc.identifier.bibliographicCitation | JACS Au, v.2, no.7, pp.1596 - 1603 | - |
dc.description.isOpenAccess | TRUE | - |
dc.subject.keywordAuthor | plasmonics | - |
dc.subject.keywordAuthor | dark-field microscopy | - |
dc.subject.keywordAuthor | super-resolution imaging | - |
dc.subject.keywordAuthor | bioimaging | - |
dc.subject.keywordAuthor | intracellular transport | - |
dc.subject.keywordAuthor | three-dimensional rotation | - |
dc.subject.keywordAuthor | endosomal tug-of-war | - |
dc.subject.keywordPlus | GOLD NANORODS | - |
dc.subject.keywordPlus | TRANSPORT | - |
dc.subject.keywordPlus | LEVY | - |
dc.subject.keywordPlus | MECHANISMS | - |
dc.subject.keywordPlus | MICROSCOPY | - |
dc.subject.keywordPlus | PATTERNS | - |
dc.subject.keywordPlus | PLATFORM | - |
dc.subject.keywordPlus | CELL | - |
dc.citation.endPage | 1603 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 1596 | - |
dc.citation.title | JACS Au | - |
dc.citation.volume | 2 | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.type.docType | Article | - |