Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김진해 | - |
dc.date.accessioned | 2023-01-10T09:40:10Z | - |
dc.date.available | 2023-01-10T09:40:10Z | - |
dc.date.created | 2022-06-29 | - |
dc.date.issued | 2022-06 | - |
dc.identifier.issn | 1226-6531 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11750/17354 | - |
dc.description.abstract | High-pressure (HP) NMR is a powerful method to elucidate various structural features of amyloidogenic proteins. Following the previous mini-review recapitulating the HP-NMR application for amyloid-β peptides of the last issue [J. H. Kim, J. Kor. Mag. Reson. Soc. 26, 17 (2022)], the recent advancements in the HP NMR application for α-synuclein (α-Syn) are briefly summarized and discussed here. Although α-Syn is a well-known intrinsically disordered protein (IDP), several studies have shown that it can also exhibit heterogeneous yet partially folded conformations, which may correlate with its amyloid-forming propensity. HP NMR has been a valuable tool for investigating the dynamic and transient structural features of α-Syn and has provided unique insights to appreciate its aggregation-prone characters. | - |
dc.language | English | - |
dc.publisher | 한국자기공명학회 | - |
dc.title | High-pressure NMR application for α-synuclein | - |
dc.title.alternative | High-pressure NMR application for α-synuclein | - |
dc.type | Article | - |
dc.identifier.doi | 10.6564/JKMRS.2022.26.2.021 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Magnetic Resonance Society, v.26, no.2, pp.21 - 23 | - |
dc.identifier.kciid | ART002847882 | - |
dc.description.isOpenAccess | FALSE | - |
dc.subject.keywordAuthor | high-pressure NMR | - |
dc.subject.keywordAuthor | α-Synuclein | - |
dc.subject.keywordAuthor | amyloid | - |
dc.subject.keywordAuthor | protein aggregation | - |
dc.subject.keywordAuthor | NMR spectroscopy | - |
dc.subject.keywordPlus | AMYLOID FIBRILS | - |
dc.subject.keywordPlus | DISSOCIATION | - |
dc.subject.keywordPlus | AGGREGATION | - |
dc.subject.keywordPlus | REVEALS | - |
dc.citation.endPage | 23 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 21 | - |
dc.citation.title | Journal of the Korean Magnetic Resonance Society | - |
dc.citation.volume | 26 | - |
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