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Non-Cross-Bridged Tetraazamacrocyclic Chelator for Stable Cu-64-Based Radiopharmaceuticals
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dc.contributor.author Dale, Ajit V. -
dc.contributor.author Pandya, Darpan N. -
dc.contributor.author Kim, Jung Young -
dc.contributor.author Lee, Hochun -
dc.contributor.author Ha, Yeong Su -
dc.contributor.author Bhatt, Nikunj -
dc.contributor.author Kim, Jonghee -
dc.contributor.author Seo, Jeong Ju -
dc.contributor.author Lee, Woonghee -
dc.contributor.author Kim, Sung Hong -
dc.contributor.author Yoon, Young-Ran -
dc.contributor.author An, Gwang Il -
dc.contributor.author Yoo, Jeongsoo -
dc.date.available 2017-07-11T06:33:17Z -
dc.date.created 2017-04-10 -
dc.date.issued 2013-10 -
dc.identifier.issn 1948-5875 -
dc.identifier.uri http://hdl.handle.net/20.500.11750/3198 -
dc.description.abstract N-mono/dimethylated TE2A tetraazamacrocycles (MM-TE2A and DM-TE2A) were synthesized in high yields. Both Cu-MM/DM-TE2A complexes showed increased kinetic stability compared to that of Cu-TE2A, whereas Cu-DM-TE2A showed even higher in vitro stability than that of Cu-ECB-TE2A. MM-TE2A and DM-TE2A were quantitatively radiolabeled with 64Cu ions and showed rapid clearance from the body to emerge as a potential efficient bifunctional chelator. © 2013 American Chemical Society. -
dc.publisher American Chemical Society -
dc.title Non-Cross-Bridged Tetraazamacrocyclic Chelator for Stable Cu-64-Based Radiopharmaceuticals -
dc.type Article -
dc.identifier.doi 10.1021/ml400142s -
dc.identifier.scopusid 2-s2.0-84885462532 -
dc.identifier.bibliographicCitation Dale, Ajit V. (2013-10). Non-Cross-Bridged Tetraazamacrocyclic Chelator for Stable Cu-64-Based Radiopharmaceuticals. ACS Medicinal Chemistry Letters, 4(10), 927–931. doi: 10.1021/ml400142s -
dc.subject.keywordAuthor Bifunctional chelator -
dc.subject.keywordAuthor copper complex -
dc.subject.keywordAuthor imaging agent -
dc.subject.keywordAuthor radiopharmaceutical -
dc.subject.keywordPlus IN-VIVO STABILITY -
dc.subject.keywordPlus COMPLEXES -
dc.subject.keywordPlus COPPER(II) -
dc.subject.keywordPlus COPPER-64 -
dc.subject.keywordPlus CYCLAM -
dc.subject.keywordPlus BIODISTRIBUTION -
dc.subject.keywordPlus MACROCYCLES -
dc.subject.keywordPlus DERIVATIVES -
dc.subject.keywordPlus CHEMISTRY -
dc.subject.keywordPlus BEHAVIOR -
dc.citation.endPage 931 -
dc.citation.number 10 -
dc.citation.startPage 927 -
dc.citation.title ACS Medicinal Chemistry Letters -
dc.citation.volume 4 -
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Lee, Hochun이호춘

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