WEB OF SCIENCE
SCOPUS
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | 김철기 | - |
| dc.contributor.author | Ali Abbas | - |
| dc.date.accessioned | 2023-03-22T19:57:46Z | - |
| dc.date.available | 2023-03-22T19:57:46Z | - |
| dc.date.issued | 2023 | - |
| dc.identifier.uri | http://hdl.handle.net/20.500.11750/45770 | - |
| dc.identifier.uri | http://dgist.dcollection.net/common/orgView/200000656095 | - |
| dc.description | Bio-functionalized particles, magnetophoresis, gradient field, Railway track, energy landscape, bio-entities. | - |
| dc.description.tableofcontents | Ⅰ. Introduction 1 1.1 Magnetic bio-functionalized cells 2 1.2 Significance of magnetic manipulation for bio-functionalized particles 3 1.3 Micromagnetic pattern for the manipulation of bio-functionalized particles 4 1.4 External field directionality and magnetic bead manipulation 5 1.5 Enhanced manipulation of bio-functionalized particles 7 1.6 Cell membrane plasticity/elasticity measurement via magnetic force 10 II. Theoretical Background 12 2.1 Various external forces for the manipulation of bio-functionalized particles 12 2.2 Magnetophoresis 13 2.3 Effective magnetic force acting on bio-functionalized particles 13 2.3.1 Gradient magnetic force 13 2.4 Various methods for the cell mechanical properties analysis 15 III. Materials and Methods 16 3.1 Materials 16 3.2 On-chip micro-patterned device fabrication 16 3.2.1 Substrate cleaning 16 3.2.2 Photolithography 17 3.2.3 Sputtering (magnetic thin film deposition) 18 3.2.4 Electrochemical deposition for disk and half-disk patterns 18 3.2.5 Teflon coating as passivation layer 19 3.3 Simulation of Railway magnetic texture for the fixed directionality 20 3.4 Bio-functionalization of magnetic particles 24 3.5 Cell conjugation with magnetic particles 25 3.5.1 Binding of HLA-A2/EpCAM antibodies to the magnetic particles 25 3.5.2 Cell Culturing and growth 25 3.5.3 Binding of cells and SPM particles 26 3.6 Experimental set-up 26 IV. Results and Discussions 28 4.1 Railway surface texture for enhanced manipulation of magnetic beads 28 4.1.1 Linear Railway-track 28 4.1.2 Classification and optimization of the Railway unit structure 29 4.1.3 Particle movement on the T and S-shaped Railway-track 31 4.1.4 Complex maze shaped Railway-track for the particle manipulation 32 4.1.5 Railway-track as a particle collector 34 4.1.6 Railway-track as an integrated particle isolator 36 4.2 Cell membrane elasticity measurement with the magnetophoretic device 39 Conclusion 43 References 44 |
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| dc.format.extent | 49 | - |
| dc.language | eng | - |
| dc.publisher | DGIST | - |
| dc.title | Enhanced magnetic manipulation of bio-functionalized cells and their membrane elasticity analysis | - |
| dc.type | Thesis | - |
| dc.identifier.doi | 10.22677/THESIS.200000656095 | - |
| dc.description.degree | Master | - |
| dc.contributor.department | Department of Physics and Chemistry | - |
| dc.identifier.bibliographicCitation | Ali Abbas. (2023). Enhanced magnetic manipulation of bio-functionalized cells and their membrane elasticity analysis. doi: 10.22677/THESIS.200000656095 | - |
| dc.contributor.coadvisor | Chun-Yeol You | - |
| dc.date.awarded | 2023-02-01 | - |
| dc.publisher.location | Daegu | - |
| dc.description.database | dCollection | - |
| dc.citation | XT.MM AL398 202302 | - |
| dc.date.accepted | 2023-03-21 | - |
| dc.contributor.alternativeDepartment | 화학물리학과 | - |
| dc.subject.keyword | Bio-functionalized particles | - |
| dc.subject.keyword | magnetophoresis | - |
| dc.subject.keyword | gradient field | - |
| dc.subject.keyword | Railway track | - |
| dc.subject.keyword | energy landscape | - |
| dc.subject.keyword | bio-entities. | - |
| dc.contributor.affiliatedAuthor | Ali Abbas | - |
| dc.contributor.affiliatedAuthor | CheolGi Kim | - |
| dc.contributor.affiliatedAuthor | Chun-Yeol You | - |
| dc.contributor.alternativeName | Ali Abbas | - |
| dc.contributor.alternativeName | CheolGi Kim | - |
| dc.contributor.alternativeName | 유천열 | - |
| dc.rights.embargoReleaseDate | 2028-02-29 | - |
